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BioActivity Data for Compound Ethidium (CID 14710)

BioActivity Outcomes:
Active(595)
 
 
Inactive(557)
 
 
Inconclusive(208)
 
 
Unspecified(378)
 
 
Top Targets:
7tm 4(27)
 
 
 
NR LBD PPAR(23)
 
 
 
 
NR LBD ER(23)
 
 
 
 
NR LBD AR(23)
 
 
 
 
NR LBD TR(15)
 
 
 
 
BioAssay Types:
Confirmatory(646)
 
 
 
 
 
Literature(537)
 
 
 
 
 
Screening(252)
 
 
 
 
Summary(71)
 
 
 
 
BioAssay Categories:
In vitro(7)
 
 
 
 
In vivo(5)
 
 
 
 
Biochemical(167)
 
 
 
 
Toxicity(80)
 
 
 
 
 
ADME(20)
 
 
 
Cell-based(142)
 
 
 
 
 
Organism-base..(8)
 
 
 
BioActivity Types:
Potency(557)
 
 
 
 
 
IC50(48)
 
 
 
 
 
AC50(16)
 
 
 
Kd(3)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1152    Data Row: 1738   Total Pages: 87   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26748838]
Potency 0.003Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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2
[SID17389015]
Potency 0.019Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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3
[SID26748838]
Potency 0.0282Confirmation screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504848, Type: confirmatory]
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4
[SID26748838]
Potency 0.0478Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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5
[SID144209709]
Potency-Replicate_1 0.0859qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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6
[SID144209709]
Potency-Replicate_1 0.0964qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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7
[SID103207558]
IC50 0.1Concentration required to inhibit 50% of human carcinoma A2780 cell lines [AID248000, Type: Literature]
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8
[SID92764758]
Potency 0.1458qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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9
[SID92764758]
Potency 0.1636qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID144209709]
Potency-Replicate_1 0.1714qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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11
[SID144204674]
Potency-Replicate_1 0.2113qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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12
[SID144204674]
Potency 0.2371qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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13
[SID144204674]
Potency 0.2661qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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14
[SID92764758]
AC50_uM 0.293Development of Small Molecule Probes of the Histone Methyltransferase, NSD2 Measured in Biochemical System Using Plate Reader - 7053-01_Inhibitor_Dose_CherryPick_Activity [AID1053173, Type: confirmatory]histone-lysine N-methyltransferase NSD2 isoform 1 [Homo sapiens] [gi:109633019]
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15
[SID144204674]
Potency-Replicate_1 0.2985qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
16
[SID144204963]
Potency 0.3264qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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17
[SID144204674]
Potency-Replicate_1 0.3758qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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18
[SID103207558]
IC50 0.4Concentration required to inhibit 50% of human carcinoma CH1 cell lines [AID247965, Type: Literature]
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19
[SID17389015]
Potency 0.4992qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia: Hit Validation [AID504374, Type: confirmatory]core-binding factor subunit beta isoform 2 [Homo sapiens] [gi:13124873]
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20
[SID17389015]
Potency 0.4992qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia: Hit Validation [AID504374, Type: confirmatory]runt-related transcription factor 1 isoform AML1b [Homo sapiens] [gi:49574546]
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