Bookmark and Share
2J-356S (CID 1470719) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(71)
 
 
Inactive(484)
 
 
Inconclusive(29)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(21)
 
 
7TM GPCR Srsx(15)
 
 
 
TRP 2(9)
 
 
 
CAP ED(5)
 
 
ANK(5)
 
 
 
 
BioAssay Types:
Screening(385)
 
 
 
 
Confirmatory(185)
 
 
 
 
 
Literature(11)
 
 
 
BioActivity Types:
Potency(123)
 
 
 
 
 
IC50(32)
 
 
 
 
EC50(16)
 
 
 
 
AC50(9)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 532    Data Row: 585   Total Pages: 30   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49666601]
Potency 0.4109qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
2
[SID49666601]
Potency 0.5174qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
3
[SID49666601]
AC50_uM 0.92Shn3: Dual-Go Shn3RL cells Measured in Cell-Based System Using Plate Reader - 2134-02_Inhibitor_Dose_CherryPick_Activity [AID624133, Type: confirmatory]
View
4
[SID49666601]
Potency 0.9285Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
View
5
[SID49666601]
Potency 0.9285Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
View
6
[SID49666601]
AbsAC35_uM 0.962Cell-based secondary assay to test the inhibitory activity of small molecule on Plasmodium flaciparum (3D7 strain) survival in red blood cells Measured in Cell-Based System Using Plate Reader - 2120-05_Inhibitor_Dose_CherryPick_Activity [AID652047, Type: confirmatory]
View
7
[SID49666601]
AC50_uM 1.83Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Based System Using Plate Reader - 2134-01_Inhibitor_Dose_CherryPick_Activity [AID624132, Type: confirmatory]
View
8
[SID49666601]
EC50 1.889Luminescence Cell-Based/Microorganism Dose Confirmation HTS to Identify Inhibitors of T.Cruzi Replication. [AID2044, Type: confirmatory]
View
9
[SID49666601]
Potency 1.9953Confirmation screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504848, Type: confirmatory]
View
10
[SID49666601]
AC50_uM 3.31ARNT-TAC3: AlphaScreen HTS to detect disruption of ARNT/TAC3 interactions Measured in Biochemical System Using Plate Reader - 2158-01_Inhibitor_Dose_CherryPick_Activity [AID651703, Type: confirmatory]aryl hydrocarbon receptor nuclear translocator [Homo sapiens] [gi:2702319]
View
11
[SID49666601]
AC50_uM 3.31ARNT-TAC3: AlphaScreen HTS to detect disruption of ARNT/TAC3 interactions Measured in Biochemical System Using Plate Reader - 2158-01_Inhibitor_Dose_CherryPick_Activity [AID651703, Type: confirmatory]transforming acidic coiled-coil-containing protein 3 [Homo sapiens] [gi:5454102]
View
12
[SID49666601]
AbsAC35_uM 3.46Cell-based secondary assay to test the inhibitory activity of small molecule on Plasmodium flaciparum (HB3 strain) survival in red blood cells Measured in Cell-Based System Using Plate Reader - 2120-06_Inhibitor_Dose_CherryPick_Activity [AID652041, Type: confirmatory]
View
13
[SID49666601]
Potency 3.5481Confirmation screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504850, Type: confirmatory]
View
14
[SID49666601]
AC50_uM 4.02Shn3: Cytotox assay Measured in Cell-Based System Using Plate Reader - 2134-03_Inhibitor_Dose_CherryPick_Activity [AID624134, Type: confirmatory]
View
15
[SID49666601]
AC50_uM 4.345Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Beta Cell Apoptosis [AID449756, Type: confirmatory]
View
16
[SID49666601]
IC50 4.464Discovery of Small Molecule Probes for H1N1 Influenza NS1A [AID504329, Type: confirmatory]nonstructural protein 1 [Influenza A virus (A/California/07/2009(H1N1))] [gi:227977143]
View
17
[SID49666601]
IC50 4.582Luminescence-based cell-based high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3) [AID624394, Type: confirmatory]photoreceptor-specific nuclear receptor [Homo sapiens] [gi:216409728]
View
18
[SID49666601]
EC50 4.736Luminescence Microorganism-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to SK(-)GAS Group A Streptococcus [AID1900, Type: confirmatory]
View
19
[SID49666601]
IC50 5.758Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3):Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) [AID624395, Type: confirmatory]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
View
20
[SID49666601]
EC50 5.781Luminescence Cell-Based Dose Response HTS Screen to Identify Cytotoxic Compounds of NIH3T3 cells. [AID2010, Type: confirmatory]
View