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BioActivity Data for Compound simetryn (CID 13905)

BioActivity Outcomes:
Active(7)
 
 
Inactive(121)
 
 
Inconclusive(15)
 
 
Unspecified(9)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD ER(9)
 
 
NR LBD TR(7)
 
 
NR LBD Fxr(6)
 
 
 
BioAssay Types:
Confirmatory(95)
 
 
 
 
Summary(24)
 
 
 
 
BioAssay Categories:
In vivo(2)
 
 
Biochemical(2)
 
 
Toxicity(18)
 
 
 
 
BioActivity Types:
Potency(111)
 
 
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 144    Data Row: 152   Total Pages: 8   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID194141176]
IC50 0.11749Inhibition of photosystem-mediated photosynthetic electron transport in Spinacia oleracea (spinach) leaf thylakoid assessed as reduction of oxygen evolution [AID1109333, Type: confirmatory]Cytochrome b6-f complex subunit 4 [gi:129864]
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2
[SID194141176]
IC50 0.47863Inhibition of photosystem-mediated photosynthetic electron transport in Scenedesmus acutus assessed as reduction of oxygen evolution [AID1109332, Type: confirmatory]
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3
[SID144211019]
Ratio Potency (uM) 34.6654qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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4
[SID194141176]
Herbicidal activity against hydroponic culture of s-triazine-susceptible Poa annua at 100 ppm after 14 days [AID1109827, Type: other]
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5
[SID194141176]
Herbicidal activity against hydroponic culture of s-triazine-susceptible Poa annua at 1000 ppm after 14 days [AID1109828, Type: other]
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6
[SID194141176]
Protection against oxyfluorfen-induced phytotoxicity in Scenedesmus acutus in light condition assessed as reduction of protoporphyrin-9 accumulation per ml of packed cell volume after 2 hr [AID1109325, Type: other]
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7
[SID194141176]
Protection against oxyfluorfen-induced phytotoxicity in Scenedesmus acutus in light condition assessed as reduction of ethane formation per ml of packed cell volume after 16 hr (Rvb = 11.82 nM) [AID1109326, Type: other]
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8
[SID194141176]
Protection against oxyfluorfen-induced phytotoxicity in Scenedesmus acutus in light condition assessed as increase of chlorophyll content after 16 hr (Rvb = 0.94 ug/ml) [AID1109327, Type: other]
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9
[SID194141176]
Protection against oxyfluorfen-induced phytotoxicity in Scenedesmus acutus in light condition assessed as cell density per micro liter of packed cell volume after 16 hr (Rvb = 2.1 ml) [AID1109328, Type: other]
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10
[SID194141176]
Phytotoxicity against Scenedesmus acutus in light condition assessed as reduction of chlorophyll content after 16 hr (Rvb = 20.25 ug/ml) [AID1109330, Type: other]
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11
[SID194141176]
Phytotoxicity against Scenedesmus acutus in light condition assessed as cell density per micro liter of packed cell volume after 16 hr (Rvb = 3.4 ml) [AID1109331, Type: other]
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12
[SID26757337]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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13
[SID194141176]
Protection against chlorophthalim-induced phytotoxicity in Scenedesmus acutus in light condition assessed as reduction of ethane formation per ml of packed cell volume after 16 hr (Rvb = 11.82 nM) [AID1109320, Type: other]
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14
[SID194141176]
Protection against chlorophthalim-induced phytotoxicity in Scenedesmus acutus in light condition assessed as reduction of protoporphyrin-9 accumulation per ml of packed cell volume after 2 hr [AID1109321, Type: other]
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15
[SID194141176]
Protection against chlorophthalim-induced phytotoxicity in Scenedesmus acutus in light condition assessed as increase of chlorophyll content after 16 hr (Rvb = 0.94 ug/ml) [AID1109322, Type: other]
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16
[SID194141176]
Protection against chlorophthalim-induced phytotoxicity in Scenedesmus acutus in light condition assessed as cell density per micro liter of packed cell volume after 16 hr (Rvb = 2.1 ml) [AID1109323, Type: other]
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17
[SID26757337]
Potency qHTS assay for small molecule agonists of the peroxisome proliferator-activated receptor alpha (PPARalpha) signaling pathway [AID651778, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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18
[SID144211019]
Ratio Potency (uM) qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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19
[SID144211019]
Potency-Replicate_1 qHTS assay for small molecule activators of the heat shock response signaling pathway [AID743210, Type: confirmatory]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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20
[SID26757337]
Potency qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway [AID651751, Type: confirmatory]pregnane X receptor [Rattus norvegicus] [gi:5702233]
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