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AGN-PC-00OCKS (CID 13891346) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Inactive(5)
 
 
Unspecified(16)
 
 
Top Targets:
PAD(5)
 
 
 
 
PAD M(2)
 
 
BioAssay Types:
Literature(16)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 18    Data Row: 22   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID118043682]
Late stage assay provider results from the probe development effort to identify inhibitors of Arginine Deiminase 4 (PAD4): colorimetric biochemical substrate assay to identify inhibitors of PAD4 [AID588559, Type: other]protein-arginine deiminase type-4 [Homo sapiens] [gi:216548487]
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2
[SID103245942]
Inhibition of recombinant wild-type PAD4 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate assessed as residual activity at 10 uM preincubated for 15 mins followed by substrate addition measured after 15 mins by COLDER assay relative to control [AID1069623, Type: Literature]Protein-arginine deiminase type-4 [gi:296439260]
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3
[SID103245942]
Inhibition of recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate assessed as residual activity at 10 uM preincubated for 15 mins followed by substrate addition measured after 15 mins by COLDER assay relative to control [AID1069625, Type: Literature]Protein-arginine deiminase type-2 [gi:7531171]
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4
[SID103245942]
Inhibition of recombinant wild-type PAD1 (unknown origin) using N-alpha-Benzoyl-L-arginine amide as substrate assessed as residual activity at 10 uM preincubated for 15 mins followed by substrate addition measured after 15 mins by COLDER assay relative to control [AID1069626, Type: Literature]Protein-arginine deiminase type-1 [gi:56757695]
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5
[SID103245942]
Inhibition of recombinant wild-type PAD3 (unknown origin) using N-alpha-Benzoyl-L-arginine amide as substrate assessed as residual activity at 10 uM preincubated for 15 mins followed by substrate addition measured after 15 mins by COLDER assay relative to control [AID1069624, Type: Literature]Protein-arginine deiminase type-3 [gi:56757696]
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6
[SID103245942]
Cytotoxic activity against mouse melanoma cell culture(B-16) [AID38038, Type: Literature]
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7
[SID103245942]
Cytotoxic activity against human lymphoblastic leukemia cell culture (CCRF-CEM) [AID44017, Type: Literature]
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8
[SID103245942]
Antimicrobial activity was determined against Candida albicans ATCC 10231 [AID44989, Type: Literature]
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9
[SID103245942]
Antimicrobial activity was determined against Escherichia coli ATCC 9637 [AID69959, Type: Literature]
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10
[SID103245942]
Cytotoxic activity against human epidermoid carcinoma of the nasopharynx (9KB) [AID70059, Type: Literature]
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11
[SID103245942]
Antimicrobial activity was determined against Klebsiella pneumoniae ATCC 10031 [AID94298, Type: Literature]
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12
[SID103245942]
Cytotoxic activity against mouse lymphoblastic leukemia cell culture (L-1210) [AID94732, Type: Literature]
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13
[SID103245942]
Antimicrobial activity was determined against Mycobacterium smegmatis ATCC 607 [AID144440, Type: Literature]
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14
[SID103245942]
Cytotoxic activity against P388 mouse leukemia cell culture (9PS(P388)) [AID152574, Type: Literature]
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15
[SID103245942]
Antimicrobial activity was determined against Pseudomonas aeruginosa ATCC 27853 cells [AID164400, Type: Literature]
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16
[SID103245942]
Antimicrobial activity was determined against Salmonella gallinarum ATCC 9184 [AID200512, Type: Literature]
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17
[SID103245942]
Antimicrobial activity was determined against Staphylococcus aureus ATCC 13709 [AID207620, Type: Literature]
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18
[SID118043682]
Late stage assay provider results from the probe development effort to identify inhibitors of PAD4: colorimetric biochemical substrate assay to identify inhibitors of PADs 1-4 [AID588560, Type: other]
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19
[SID118043682]
Late stage assay provider results from the probe development effort to identify inhibitors of PAD4: colorimetric biochemical substrate assay to identify inhibitors of PADs 1-4 [AID588560_1, Type: other]protein-arginine deiminase type-1 [Homo sapiens] [gi:122056685]
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20
[SID118043682]
Late stage assay provider results from the probe development effort to identify inhibitors of PAD4: colorimetric biochemical substrate assay to identify inhibitors of PADs 1-4 [AID588560_2, Type: other]protein-arginine deiminase type-2 [Homo sapiens] [gi:122939159]
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