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hexamethylsilazane (CID 13838) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(199)
 
 
Inconclusive(11)
 
 
Unspecified(1)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD AR(16)
 
 
NR LBD ER(16)
 
 
 
 
NR LBD Fxr(10)
 
 
 
NR LBD VDR(10)
 
 
 
BioAssay Types:
Confirmatory(155)
 
 
 
 
Summary(48)
 
 
 
BioActivity Types:
Potency(191)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 119    Data Row: 213   Total Pages: 11   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209626]
Potency-Replicate_1 0.0864qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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2
[SID144209626]
Ratio Potency (uM) 0.136875qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID26757785]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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4
[SID144209626]
Potency-Replicate_1 54.4909qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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5
[SID144213598]
Potency-Replicate_1 68.5896qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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6
[SID144209626]
Potency-Replicate_1 qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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7
[SID144213598]
Potency-Replicate_1 qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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8
[SID569070]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID330, Type: other]
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9
[SID144209626]
Potency-Replicate_1 qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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10
[SID144209626]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway: Summary [AID743241, Type: summary]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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11
[SID144213598]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway: Summary [AID743241, Type: summary]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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12
[SID144209626]
qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway: Summary [AID743242, Type: summary]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
13
[SID144213598]
qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway: Summary [AID743242, Type: summary]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
14
[SID144209626]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
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15
[SID144213598]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
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16
[SID144209626]
Potency-Replicate_1 qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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17
[SID144213598]
Potency-Replicate_1 qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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18
[SID144209626]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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19
[SID144213598]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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20
[SID144209626]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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