Bookmark and Share
2-(pyridin-2-ylamino)quinolin-8-ol (CID 1380879) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(146)
 
 
Inactive(733)
 
 
Inconclusive(34)
 
 
Unspecified(13)
 
 
Top Targets:
7TM GPCR Srx(26)
 
 
7TM GPCR Srsx(23)
 
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
Death TRAILR..(12)
 
 
 
 
BioAssay Types:
Screening(616)
 
 
 
 
 
Confirmatory(270)
 
 
 
 
 
Literature(18)
 
 
 
 
BioActivity Types:
Potency(162)
 
 
 
 
 
IC50(59)
 
 
 
 
EC50(24)
 
 
 
 
AC50(10)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 838    Data Row: 926   Total Pages: 47   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID131333465]
IC50 0.1415Novartis GNF Liver Stage Dataset: Malariabox Annotation [AID602156, Type: Literature]
View
2
[SID103656252]
IC50 0.1415NOVARTIS: Antimalarial liver stage activity measured as reduction in Plasmodium yoelii schizont area in HepG2-A16-CD81 cells by immuno-fluorescence, and median schizont size at 10uM compound concentration [AID602119, Type: Literature]
View
3
[SID7978378]
AbsAC35_uM 0.182Cell-based secondary assay to test the inhibitory activity of small molecule on Plasmodium flaciparum (3D7 strain) survival in red blood cells Measured in Cell-Based System Using Plate Reader - 2120-05_Inhibitor_Dose_CherryPick_Activity [AID652047, Type: confirmatory]
View
4
[SID103656252]
EC50 0.3023NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay [AID449704, Type: Literature]
View
5
[SID7978378]
AbsAC35_uM 0.321Cell-based secondary assay to test the inhibitory activity of small molecule on Plasmodium flaciparum (HB3 strain) survival in red blood cells Measured in Cell-Based System Using Plate Reader - 2120-06_Inhibitor_Dose_CherryPick_Activity [AID652041, Type: confirmatory]
View
6
[SID7978378]
Potency 0.3696Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
View
7
[SID103656252]
EC50 0.679NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in erythrocyte-based infection assay [AID449703, Type: Literature]
View
8
[SID7978378]
EC50 0.713High Throughput Screen to Identify Compounds that Suppress the Growth of Human Colon Tumor Cells Lacking Oncogenic Beta Catenin Expression - Dose Response [AID1045, Type: confirmatory]
View
9
[SID7978378]
EC50 1.122Luminescence Cell-Based/Microorganism Dose Confirmation HTS to Identify Inhibitors of T.Cruzi Replication. [AID2044, Type: confirmatory]
View
10
[SID7978378]
Potency 1.122qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
View
11
[SID7978378]
AC50_uM 1.181Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Beta Cell Apoptosis [AID449756, Type: confirmatory]
View
12
[SID7978378]
EC50 1.234High Throughput Screen to Identify Compounds that Suppress the Growth of Cells with a Deletion of the PTEN Tumor Suppressor - Dose Response [AID1047, Type: confirmatory]
View
13
[SID7978378]
EC50 1.549Fluorescence Cell-Based Retest of C. albicans Growth in the Presence of Fluconazole [AID2467, Type: confirmatory]
View
14
[SID7978378]
Potency 1.636qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
15
[SID7978378]
EC50 1.75A cytotoxicity screen of small molecule inhibitors of the PhoP regulon in Salmonella typhi identified in the primary screen [AID2252, Type: confirmatory]
View
16
[SID7978378]
EC50 2.16A cytotoxicity screen of small molecule inhibitors of the PhoP regulon in Salmonella typhimurium identified in the primary screen [AID2253, Type: confirmatory]
View
17
[SID7978378]
AC50_uM 2.273ATP-based Luminescence in the Absence of Cytokines Measured in Cell-Based System Using Plate Reader - 2061-06_Inhibitor_Dose_CherryPick [AID463229, Type: confirmatory]
View
18
[SID7978378]
IC50 2.345Discovery of Small Molecule Probes for H1N1 Influenza NS1A [AID504329, Type: confirmatory]nonstructural protein 1 [Influenza A virus (A/California/07/2009(H1N1))] [gi:227977143]
View
19
[SID7978378]
IC50 2.35HTS Counterscreen for Detection of Compound Cytotoxicity in MIN6 Cells [AID2122, Type: confirmatory]
View
20
[SID7978378]
EC50 2.354Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole [AID2423, Type: confirmatory]heat shock protein 90 [Candida albicans] [gi:994798]
View