Bookmark and Share
Aminolevulinic Acid (CID 137) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(12)
 
 
Inactive(472)
 
 
Inconclusive(3)
 
 
Unspecified(92)
 
 
Top Targets:
7tm 4(35)
 
 
Esterase lipa..(5)
 
 
TRP 2(5)
 
 
CAP ED(5)
 
 
Troponin(4)
 
 
BioAssay Types:
Screening(345)
 
 
 
Confirmatory(112)
 
 
 
 
Literature(110)
 
 
 
 
BioActivity Types:
Potency(97)
 
 
 
 
IC50(18)
 
 
 
 
Ki(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 537    Data Row: 579   Total Pages: 29   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103182993]
IC50 12.9Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp method [AID406571, Type: Literature]Gamma-aminobutyric acid receptor subunit rho-1 [gi:223590210]
View
2
[SID56322917]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
View
3
[SID103182993]
Increase in ROS production in human U251 cells at 100 uM after 4 hrs by FACS [AID347396, Type: Literature]
View
4
[SID103182993]
Inhibition of 26S proteasome activity in human U251 cells at 1 mM after 48 hrs [AID347411, Type: Literature]
View
5
[SID103182993]
Induction of apoptosis in human U251 cells assessed as increase in full length caspase 8 level after 24 hrs by Western blot [AID347584, Type: Literature]
View
6
[SID103182993]
Increase in heme level in human U251 cells assessed as porphobilinogen deaminase level at 100 uM after 2 hrs by Western blot in presence of cycloheximide [AID347405, Type: Literature]
View
7
[SID103182993]
Antibacterial activity against Escherichia coli K-12 assessed as reduction in microbial viability incubated at 0.1 mM followed by irradiation at 120 J.cm2 light [AID519379, Type: Literature]
View
8
[SID103182993]
Antibacterial activity against Escherichia coli K-12 assessed as reduction in microbial viability incubated at 40 mM followed by irradiation at 120 J.cm2 light [AID519380, Type: Literature]
View
9
[SID103182993]
Induction of photoactive porphyrins in Escherichia coli K-12 exposed to irradiation at 120 J.cm2 light by HPLC [AID519381, Type: Literature]
View
10
[SID103182993]
Induction of photoactive porphyrins in Escherichia coli K-12 assessed as uroporphyrin level exposed to irradiation at 120 J.cm2 light by HPLC [AID519382, Type: Literature]
View
11
[SID103182993]
Induction of photoactive porphyrins in Escherichia coli K-12 assessed as protoporphyrin level exposed to irradiation at 120 J.cm2 light by HPLC [AID519383, Type: Literature]
View
12
[SID103182993]
Antibacterial activity against Escherichia coli K-12 assessed as reduction in microbial viability incubated at 40 mM for 4 hrs under dark condition [AID519389, Type: Literature]
View
13
[SID103182993]
Ki 230TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cells [AID681124, Type: Literature]Solute carrier family 15 member 2 [gi:2499990]
View
14
[SID103182993]
Km 253The Michaelis-Menten rate of reaction catalyzed by ALA dehydratase from Bacillus subtilis measured spectrophotometrically [AID31307, Type: confirmatory]
View
15
[SID103182993]
Ki 790Inhibition constant (Ki) for human intestinal peptide carrier [AID92023, Type: Literature]
View
16
[SID103182993]
Ki 960Inhibitory activity against porcine kidney prolidase [AID162623, Type: confirmatory]
View
17
[SID103182993]
IC50 1570Cytotoxicity against human HL60 cells after 72 hrs by MTT assay [AID347393, Type: Literature]
View
18
[SID103182993]
IC50 1735Cytotoxicity against human MCF7 cells after 72 hrs by Hoechst test [AID347394, Type: Literature]
View
19
[SID103182993]
Ki 2200TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT1-expressing LLC-PK1 cells [AID681125, Type: Literature]Solute carrier family 15 member 1 [gi:1730492]
View
20
[SID103182993]
IC50 2665Cytotoxicity against human U251 cells after 72 hrs by Hoechst test [AID347392, Type: Literature]
View