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4-hydroxybenzoic acid (CID 135) - Compound BioActivity Data
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BioActivity Outcomes:
Active(36)
 
 
Inactive(218)
 
 
Inconclusive(9)
 
 
Unspecified(116)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
NR LBD ER(14)
 
 
NR LBD AR(14)
 
 
alpha CA I II..(10)
 
 
 
NR LBD VDR(9)
 
 
BioAssay Types:
Literature(151)
 
 
 
 
 
Confirmatory(149)
 
 
 
Summary(48)
 
 
 
Screening(5)
 
 
BioActivity Types:
Potency(185)
 
 
 
Ki(37)
 
 
 
IC50(23)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 282    Data Row: 379   Total Pages: 19   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103176360]
IC50 0.2Antihemorrhagic activity in ddY mouse assessed as inhibition of Protobothrops flavoviridis venom-induced hemorrhagic lesion formation compound incubated with venom for 10 mins and administered subcutaneously measured after 24 hrs [AID631927, Type: Literature]
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2
[SID103176360]
Ki 0.87Inhibition of human CA2 by stopped-flow CO2 hydration assay [AID462271, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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3
[SID103176360]
Ki 0.92Inhibition of human CA1 by stopped-flow CO2 hydration assay [AID462270, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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4
[SID103176360]
Ki 3.67Inhibition of human CA5A by stopped-flow CO2 hydration assay [AID462274, Type: Literature]Carbonic anhydrase 5A, mitochondrial [gi:461680]
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5
[SID103176360]
Ki 3.73Inhibition of human CA9 by stopped-flow CO2 hydration assay [AID462278, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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6
[SID46394367]
Ki 4Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Structure Of Protocatechuate 3,4-Dioxygenase Complexed With 3-Chloro- 4-Hydroxybenzoate [gi:2780842]
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7
[SID46394367]
Ki 4Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Structure Of Protocatechuate 3,4-Dioxygenase Complexed With 3-Chloro- 4-Hydroxybenzoate [gi:2780842]
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8
[SID46394367]
Ki 4Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain M, Structure Of Protocatechuate 3,4-Dioxygenase Complexed With 3-Chloro- 4-Hydroxybenzoate [gi:2780843]
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9
[SID46394367]
Ki 4Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain M, Structure Of Protocatechuate 3,4-Dioxygenase Complexed With 3-Chloro- 4-Hydroxybenzoate [gi:2780843]
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10
[SID103176360]
Ki 4.08Inhibition of human CA7 by stopped-flow CO2 hydration assay [AID462277, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
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11
[SID103176360]
Ki 4.8Inhibition of human carbonic anhydrase 12 catalytic domain by stopped-flow CO2 hydration assay [AID342484, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
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12
[SID103176360]
Ki 5.7Inhibition of human CA6 by stopped-flow CO2 hydration assay [AID462276, Type: Literature]Carbonic anhydrase 6 [gi:116241278]
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13
[SID103176360]
Ki 6.16Inhibition of human CA14 by stopped-flow CO2 hydration assay [AID462281, Type: Literature]Carbonic anhydrase 14 [gi:8928036]
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14
[SID103176360]
Ki 6.27Inhibition of human CA12 by stopped-flow CO2 hydration assay [AID462279, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
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15
[SID103176360]
Ki 6.61Inhibition of human CA3 by stopped-flow CO2 hydration assay [AID462272, Type: Literature]Carbonic anhydrase 3 [gi:134047703]
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16
[SID103176360]
Ki 7.13Inhibition of human CA5B by stopped-flow CO2 hydration assay [AID462275, Type: Literature]Carbonic anhydrase 5B, mitochondrial [gi:8928041]
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17
[SID103176360]
Ki 7.78Inhibition of human CA4 by stopped-flow CO2 hydration assay [AID462273, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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18
[SID103176360]
Ki 7.79Inhibition of mouse CA13 by stopped-flow CO2 hydration assay [AID462280, Type: Literature]Carbonic anhydrase 13 [gi:30580372]
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19
[SID103176360]
Ki 8.46Inhibition of Dicentrarchus labrax CA using 4-nitrophenylacetate substrate by esterase assay [AID607497, Type: Literature]Carbonic anhydrase [gi:123910379]
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20
[SID103176360]
Ki 9.2Inhibition of human carbonic anhydrase 5A by stopped-flow CO2 hydration assay [AID342479, Type: Literature]Carbonic anhydrase 5A, mitochondrial [gi:461680]
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