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diphenyl disulfide (CID 13436) - Compound BioActivity Data
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BioActivity Outcomes:
Active(20)
 
 
Inactive(829)
 
 
Inconclusive(23)
 
 
Unspecified(3)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(21)
 
 
NR LBD PPAR(14)
 
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
BioAssay Types:
Screening(518)
 
 
 
 
Confirmatory(283)
 
 
 
 
 
Literature(25)
 
 
 
 
Summary(25)
 
 
 
 
BioActivity Types:
Potency(244)
 
 
 
 
 
IC50(44)
 
 
 
 
EC50(9)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 798    Data Row: 875   Total Pages: 44   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103592655]
IC50 0.65Inhibition of Plasmodium falciparum KAS3 expressed in Escherichia coli assessed as transfer of [1-14C]acetyl-CoA to [1-14C]acetyl-ACP [AID345868, Type: Literature]
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2
[SID8139960]
Potency 1.0621qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
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3
[SID103592655]
IC50 5Antimalarial activity against chloroquine-resistant Plasmodium falciparum D6 by [3H]hypoxanthine uptake [AID345870, Type: Literature]
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4
[SID103592655]
IC50 6.7Antimalarial activity against chloroquine-sensitive Plasmodium falciparum W2 by [3H]hypoxanthine uptake [AID345869, Type: Literature]
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5
[SID8139960]
Potency 11.5821qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID8139960]
Potency 11.5821qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID8139960]
Potency 12.5893qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1468, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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8
[SID144207926]
Ratio Potency (uM) 17.4972qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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9
[SID8139960]
Potency 25.1189qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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10
[SID144207926]
Potency-Replicate_1 27.5005qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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11
[SID8139960]
Potency 31.6228Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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12
[SID8139960]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions. [AID1504, Type: summary]GNAO1 protein [Homo sapiens] [gi:34190601]
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13
[SID69306]
NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain [AID161, Type: other]
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14
[SID69306]
NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
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15
[SID8139960]
uHTS identification of small molecule activators of the adaptive arm of the Unfolded Protein response via a luminescent-based reporter assay [AID463104, Type: screening]
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16
[SID8139960]
Screen for Chemicals that Extend Yeast Lifespan [AID775, Type: screening]
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17
[SID48415323]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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18
[SID8139960]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. [AID1441, Type: screening]guanine nucleotide-binding protein G(o) subunit alpha isoform a [Homo sapiens] [gi:10567816]
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19
[SID8139960]
qHTS for Inhibitors of Inflammasome Signaling: IL-1-beta AlphaLISA Primary Screen [AID743279, Type: screening]interleukin-1 beta proprotein [Homo sapiens] [gi:10835145]
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20
[SID8139960]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. [AID1441, Type: screening]regulator of G-protein signaling 16 [Homo sapiens] [gi:156416009]
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