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CHEMBL29804 (CID 13409348) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Inconclusive(1)
 
 
Unspecified(3)
 
 
Top Targets:
Chemokine CXC(1)
 
 
BioAssay Types:
Literature(5)
 
 
 
 
BioActivity Types:
IC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103198657]
IC50 0.013Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay [AID426392, Type: Literature]Interleukin-8 [gi:124359]
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2
[SID103198657]
Reduction in paw swelling at 200 mg/kg po dose in rat using rat paw carrageenan test;NT means not tested. [AID189384, Type: Literature]
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3
[SID103198657]
Cytotoxicity against of human polymorphonuclear leukocytes assessed as cell viability by trypan blue dye exclusion assay [AID426393, Type: Literature]
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4
[SID103198657]
Cytotoxicity against mouse L1.2 cells assessed as cell viability by trypan blue dye exclusion assay [AID426478, Type: Literature]
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5
[SID103198657]
Potency relative to [2-(2,4-Dichloro-phenoxy)-phenyl]-acetic acid in rat adjuvant arthritis test;ND means no data. [AID187303, Type: Literature]
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