3-chloro-2-(2,3-dihydro-2-oxo-1,3,4-oxadiazol-5-yl)benzo(b)thiophene
(CID
132875
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
1
)
Unspecified(2)
BioAssay Types:
Literature(
3
)
BioActivity Types:
IC50(
1
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 3 Data Row: 3 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
103189437
]
Active
IC50
0.2
Concentration required to inhibit antigen-induced release of histamine (AIR) by 50% from rat peritoneal mast cells (RMC) (in vitro) [AID
155968
, Type: Literature]
View
X
Row No.
1
Structure
Substance
SID
103189437
CID
132875
Outcome
Active
IC50
0.2 [uM]
BioAssay
Concentration required to inhibit antigen-induced release of histamine (AIR) by 50% from rat peritoneal mast cells (RMC) (in vitro)
AID
155968
BioAssay type
Literature
Target
PubMed
6198518
Data Table
2
[SID
103189437
]
Unspecified
Inhibition of antigen-induced release of histamine (AIR) by 50% in rat dosed perorally [AID
176902
, Type: Literature]
View
X
Row No.
2
Structure
Substance
SID
103189437
CID
132875
Outcome
Unspecified
BioAssay
Inhibition of antigen-induced release of histamine (AIR) by 50% in rat dosed perorally
AID
176902
BioAssay type
Literature
Target
PubMed
6198518
Data Table
3
[SID
103189437
]
Unspecified
Percent inhibition of antigen-induced release of histamine (AIR) at a dose of 25 mg/kg administered orally. [AID
181343
, Type: Literature]
View
X
Row No.
3
Structure
Substance
SID
103189437
CID
132875
Outcome
Unspecified
BioAssay
Percent inhibition of antigen-induced release of histamine (AIR) at a dose of 25 mg/kg administered orally.
AID
181343
BioAssay type
Literature
Target
PubMed
6198518
Data Table
Chemical Probe 
Active 
Inactive 
Inconclusive 
Unspecified 
