PHENFORMIN HYDROCHLORIDE (CID 13266) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(21)
 
 
Inactive(1132)
 
 
Inconclusive(70)
 
 
Unspecified(6)
 
 
Top Targets:
7TM GPCR Srx(20)
 
 
NR LBD PPAR(16)
 
 
 
 
alkPPc(14)
 
 
Bcl-2 like(11)
 
 
7TM GPCR Srsx(11)
 
 
BioAssay Types:
Screening(551)
 
 
 
Confirmatory(392)
 
 
 
 
 
Literature(73)
 
 
 
 
BioActivity Types:
Potency(293)
 
 
 
 
 
IC50(39)
 
 
EC50(11)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 895    Data Row: 1229   Total Pages: 25   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56463711]
Potency 3.1623qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
View
2
[SID144204035]
Potency 6.3962qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]
View
3
[SID56463711]
Potency 8.1995qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]
View
4
[SID144204736]
Potency 11.8856qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]
View
5
[SID56463711]
Potency 12.9953Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
View
6
[SID56463711]
Potency 12.9953Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
View
7
[SID56463711]
Potency 12.9953Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
View
8
[SID56463711]
Potency 12.9953Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
View
9
[SID17389768]
Potency 16.7855qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
View
10
[SID17389768]
Potency 16.7855qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
View
11
[SID17389768]
Potency 16.7855qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
View
12
[SID17389768]
Potency 16.7855qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
View
13
[SID17389768]
Potency 16.7855qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
View
14
[SID26757813]
Potency 35.4813qHTS assay for small molecule agonists of the peroxisome proliferator-activated receptor alpha (PPARalpha) signaling pathway [AID651778, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
View
15
[SID26757813]
Potency 35.4813qHTS assay for small molecule agonists of the peroxisome proliferator-activated receptor alpha (PPARalpha) signaling pathway [AID651778, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
View
16
[SID17389768]
Potency 37.578qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
View
17
[SID17389768]
Potency 37.578qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
View
18
[SID17389768]
Potency 37.578qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
View
19
[SID17389768]
Potency 37.578qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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20
[SID10321582]
 MDR-1 [AID377, Type: other]ABCB1 gene product [Homo sapiens] [gi:42741659]
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21
[SID10321582]
 MDR-1 [AID377, Type: other]ABCB1 gene product [Homo sapiens] [gi:42741659]
View
22
[SID10321582]
 MDR-1 [AID377, Type: other]ABCB1 gene product [Homo sapiens] [gi:42741659]
View
23
[SID26757813]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
View
24
[SID26757813]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
View
25
[SID17389768]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
View
26
[SID17389768]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
View
27
[SID26757813]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
View
28
[SID26757813]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
View
29
[SID17389768]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
View
30
[SID17389768]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
View
31
[SID17389768]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
View
32
[SID17389768]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
View
33
[SID17389768]
 Cell Viability - N2a [AID540, Type: confirmatory]
View
34
[SID56422460]
 Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
View
35
[SID17389768]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
View
36
[SID17389768]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812, Type: other]
View
37
[SID17389768]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
38
[SID26757813]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
39
[SID17389768]
 Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813, Type: other]
View
40
[SID56463711]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
41
[SID56463711]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
42
[SID17389768]
Potency 8.9125qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
View
43
[SID17389768]
Potency 12.5893qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
44
[SID17389768]
Potency 12.5893qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
45
[SID17389768]
Potency 12.5893qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
46
[SID855734]
Potency 35.4813qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
View
47
[SID855734]
Potency 35.4813qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
View
48
[SID56463711]
Potency 63.0957HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID540317, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
View
49
[SID17389768]
Potency 79.4328qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway [AID651751, Type: confirmatory]pregnane X receptor [Rattus norvegicus] [gi:5702233]
View
50
[SID26757813]
Potency qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway [AID651751, Type: confirmatory]pregnane X receptor [Rattus norvegicus] [gi:5702233]
View