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N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide (CID 132496) - Compound BioActivity Data
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BioActivity Outcomes:
Active(48)
 
 
Inactive(691)
 
 
Inconclusive(73)
 
 
Unspecified(27)
 
 
Top Targets:
7tm 4(43)
 
 
 
 
p450(12)
 
 
 
 
ANK(11)
 
 
 
PLDc mTdp1 2(9)
 
 
 
 
GH27(8)
 
 
BioAssay Types:
Confirmatory(422)
 
 
 
 
 
Screening(343)
 
 
 
 
Literature(54)
 
 
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(365)
 
 
 
 
 
IC50(37)
 
 
 
 
Ki(3)
 
 
Kd(1)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 654    Data Row: 839   Total Pages: 42   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103259311]
EC50 0.003Concentration required to stimulate pregnenolone formation in the mitochondria of C6-2B glioma cells. [AID44631, Type: Literature]
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2
[SID103259311]
Kd 0.004Binding affinity to human PBR [AID408746, Type: Literature]Translocator protein [gi:313104268]
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3
[SID103259311]
Ki 0.0044Binding affinity was determined as the ability to displace [3H]4''CD from the (mDRC) mitochondrial DBI receptor complex using primary cultures of glial cells [AID126589, Type: Literature]
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4
[SID103259311]
Ki 0.0044Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells [AID221360, Type: Literature]Translocator protein [gi:130253]
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5
[SID103259311]
Ki 0.005Displacement of [3H]PK11195 from TSPO in rat cortex [AID368146, Type: Literature]Translocator protein [gi:130253]
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6
[SID103259311]
IC50 0.01Displacement of [3H]PK11195 binding from peripheral benzodiazepine receptor in MA-10 mouse tumor Leydig cells [AID42148, Type: Literature]Translocator protein [gi:1730586]
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7
[SID103259311]
IC50 0.01Displacement of [3H]PK11195 binding from peripheral benzodiazepine receptor in C6 rat glioma cell line [AID42313, Type: Literature]Translocator protein [gi:130253]
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8
[SID11113625]
Potency 2.5119qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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9
[SID103259311]
IC50 3.16228Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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10
[SID50104521]
Potency 3.5481qHTS for differential inhibitors of proliferation of Plasmodium falciparum line W2 [AID1883, Type: confirmatory]
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11
[SID85231015]
Potency 3.6964Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID488745, Type: confirmatory]
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12
[SID103259311]
IC50 3.98107Antiplasmodial activity against Plasmodium falciparum GB4 after 72 hrs by SYBR green assay [AID524794, Type: Literature]
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13
[SID50104521]
Potency 3.9811qHTS for differential inhibitors of proliferation of Plasmodium falciparum line GB4 [AID1816, Type: confirmatory]
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14
[SID11113625]
Potency 3.9811qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19 [AID899, Type: confirmatory]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
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15
[SID103259311]
IC50 5.01187Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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16
[SID50104521]
Potency 5.0119qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 3D7 [AID1876, Type: confirmatory]
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17
[SID50104521]
Potency 5.0119qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 7G8 [AID1815, Type: confirmatory]
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18
[SID85231015]
Potency 5.2213Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID488752, Type: confirmatory]
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19
[SID56463201]
Potency 5.8584Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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20
[SID103259311]
IC50 6.30957Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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