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1,10-phenanthroline (CID 1318) - Compound BioActivity Data
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BioActivity Outcomes:
Active(332)
 
 
Inactive(1044)
 
 
Inconclusive(260)
 
 
Unspecified(39)
 
 
Top Targets:
7tm 4(57)
 
 
 
NR LBD PPAR(27)
 
 
 
 
NR LBD ER(17)
 
 
 
 
NR LBD AR(16)
 
 
 
 
ANK(14)
 
 
 
 
BioAssay Types:
Confirmatory(774)
 
 
 
 
 
Screening(559)
 
 
 
 
Literature(78)
 
 
 
 
 
Summary(50)
 
 
 
 
BioActivity Types:
Potency(638)
 
 
 
 
 
IC50(75)
 
 
 
 
 
EC50(27)
 
 
 
 
AC50(2)
 
 
Ki(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1133    Data Row: 1675   Total Pages: 84   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID90341127]
Potency 0.0465High Content Imaging Cell-Based qHTS for Inhibitors of the mTORC1 Signaling Pathway in MEF Cells [AID2667, Type: confirmatory]serine/threonine-protein kinase mTOR [Homo sapiens] [gi:4826730]
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2
[SID144213428]
Potency-Replicate_1 0.1737qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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3
[SID11533040]
Potency 0.2512qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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4
[SID144213428]
Potency-Replicate_1 0.389qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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5
[SID144213428]
Potency-Replicate_1 0.4364qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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6
[SID144213428]
Potency-Replicate_1 0.4897qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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7
[SID144209196]
Ratio Potency (uM) 0.646604qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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8
[SID144213428]
Potency-Replicate_1 0.6917qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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9
[SID144209196]
Potency-Replicate_1 0.6982qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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10
[SID144213428]
Ratio Potency (uM) 0.718726qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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11
[SID144209196]
Potency-Replicate_1 0.7834qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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12
[SID11533040]
IC50 0.902Discovery of Small Molecule Probes for H1N1 Influenza NS1A [AID504329, Type: confirmatory]nonstructural protein 1 [Influenza A virus (A/California/07/2009(H1N1))] [gi:227977143]
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13
[SID50105542]
Potency 1qHTS for differential inhibitors of proliferation of Plasmodium falciparum line W2 [AID1883, Type: confirmatory]
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14
[SID144209196]
Ratio Potency (uM) 1.0248qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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15
[SID50105542]
Potency 1.122qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia: Hit Validation [AID504374, Type: confirmatory]core-binding factor subunit beta isoform 2 [Homo sapiens] [gi:13124873]
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16
[SID50105542]
Potency 1.122qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia: Hit Validation [AID504374, Type: confirmatory]runt-related transcription factor 1 isoform AML1b [Homo sapiens] [gi:49574546]
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17
[SID103214027]
IC50 1.25893Binding affinity to Zn(II) after 2 hrs using FluoZin-3 by fuorescence assay [AID716293, Type: Literature]
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18
[SID144209196]
Potency-Replicate_1 1.3811qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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19
[SID144209196]
Potency-Replicate_1 1.3811qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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20
[SID144213428]
Potency-Replicate_1 1.5355qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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