dexpanthenol (CID 131204) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Inactive(191)
 
 
Inconclusive(1)
 
 
Unspecified(133)
 
 
Top Targets:
7TM GPCR Srx(12)
 
 
7TM GPCR Srsx(10)
 
 
p450(10)
 
 
 
Menin(4)
 
 
Tubulin-bindi..(4)
 
 
BioAssay Types:
Confirmatory(115)
 
 
 
Literature(64)
 
 
 
Screening(8)
 
 
BioActivity Types:
IC50(117)
 
 
 
Potency(109)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 222    Data Row: 325   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID29215203]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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2
[SID103770962]
IC50 DRUGMATRIX: Nicotinic Acetylcholine radioligand binding (ligand: [125I] Epibatidine) [AID625158, Type: other]
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3
[SID103770962]
 DRUGMATRIX: Phorbol Ester radioligand binding (ligand: [3H] PDBu) [AID625164, Type: other]
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4
[SID103770962]
IC50 DRUGMATRIX: Phosphodiesterase PDE3 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625165, Type: other]
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5
[SID103770962]
IC50 DRUGMATRIX: Phosphodiesterase PDE4 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625166, Type: other]
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6
[SID103770962]
 DRUGMATRIX: Platelet-Derived Growth Factor (PDGF) radioligand binding (ligand: [125I] PDGF) [AID625169, Type: other]
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7
[SID103770962]
IC50 DRUGMATRIX: Potassium Channel [KATP] radioligand binding (ligand: [3H] Glyburide) [AID625170, Type: other]
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8
[SID103770962]
 DRUGMATRIX: Purinergic P2X radioligand binding (ligand: [3H] alpha, beta-Methylene-ATP) [AID625189, Type: other]
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9
[SID103770962]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT1A radioligand binding (ligand: [3H] 8-OH-DPAT) [AID625190, Type: other]
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10
[SID103770962]
IC50 DRUGMATRIX: Sodium/nucleoside co-transporter radioligand binding (ligand: nitrobenzylthioinosine) [AID625197, Type: other]
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11
[SID103770962]
IC50 DRUGMATRIX: ATPase, Na+/K+ enzyme inhibition (substrate: ATP) [AID625210, Type: other]
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12
[SID103770962]
 DRUGMATRIX: Atrial Natriuretic Factor (ANF) radioligand binding (ligand: [125I] ANF (rat)) [AID625211, Type: other]
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13
[SID103770962]
IC50 DRUGMATRIX: beta-Lactamase enzyme inhibition (substrate: Nitrocefin) [AID625212, Type: other]
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14
[SID103770962]
IC50 DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT3 radioligand binding (ligand: [3H] GR-65630) [AID625219, Type: other]
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15
[SID103770962]
IC50 DRUGMATRIX: Sigma2 radioligand binding (ligand: [3H] Ifenprodil) [AID625224, Type: other]
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16
[SID103770962]
IC50 DRUGMATRIX: Sodium Channel, Site 2 radioligand binding (ligand: [3H] Batrachotoxin) [AID625225, Type: other]
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17
[SID103770962]
 DRUGMATRIX: Tumor Necrosis Factor (TNF), Non-Selective radioligand binding (ligand: [125I] TNF-alpha) [AID625230, Type: other]
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18
[SID103770962]
IC50 DRUGMATRIX: Calcium Channel Type L, Phenylalkylamine radioligand binding (ligand: [3H] (-)-Desmethoxyverapamil (D-888)) [AID625234, Type: other]
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19
[SID103770962]
IC50 DRUGMATRIX: Calcium Channel Type L, Dihydropyridine radioligand binding (ligand: [3H] Nitrendipine) [AID625216, Type: other]
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20
[SID103770962]
IC50 DRUGMATRIX: Calcium Channel Type L, Benzothiazepine radioligand binding (ligand: [3H] Diltiazem) [AID625215, Type: other]
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21
[SID103770962]
IC50 DRUGMATRIX: GABAA, Muscimol, Central radioligand binding (ligand: [3H] Muscimol) [AID625260, Type: other]
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22
[SID103770962]
IC50 DRUGMATRIX: GABAA, Flunitrazepam, Central radioligand binding (ligand: [3H] Flunitrazepam) [AID625261, Type: other]
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23
[SID103770962]
IC50 DRUGMATRIX: GABAA, Chloride Channel, TBOB radioligand binding (ligand: [3H] TBOB) [AID625262, Type: other]
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24
[SID103770962]
IC50 DRUGMATRIX: Glutamate, AMPA radioligand binding (ligand: [3H] AMPA) [AID625264, Type: other]
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25
[SID103770962]
 DRUGMATRIX: Glutamate, Kainate radioligand binding (ligand: [3H] Kainic acid) [AID625265, Type: other]
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26
[SID103770962]
IC50 DRUGMATRIX: Glutamate, NMDA, Agonism radioligand binding (ligand: [3H] CGP-39653) [AID625266, Type: other]
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27
[SID103770962]
IC50 DRUGMATRIX: Glutamate, NMDA, Phencyclidine radioligand binding (ligand: [3H] TCP) [AID625267, Type: other]
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28
[SID103770962]
IC50 DRUGMATRIX: Glycine, Strychnine-Sensitive radioligand binding (ligand: [3H] Strychnine) [AID625268, Type: other]
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29
[SID103770962]
IC50 DRUGMATRIX: Imidazoline I2, Central radioligand binding (ligand: [3H] Idazoxan) [AID625272, Type: other]
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30
[SID103770962]
 DRUGMATRIX: Interleukin IL-1 radioligand binding (ligand: [125I] interleukin 1beta) [AID625274, Type: other]
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31
[SID103770962]
IC50 DRUGMATRIX: Leukotriene, BLT (LTB4) radioligand binding (ligand: [3H]LTB4) [AID625275, Type: other]
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32
[SID103770962]
IC50 DRUGMATRIX: Acetylcholinesterase enzyme inhibition (substrate: acetylthiocholine) [AID625193, Type: other]Acetylcholinesterase [gi:113037]
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33
[SID103770962]
IC50 DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX) [AID625194, Type: other]Adenosine receptor A [gi:231473]
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34
[SID103770962]
IC50 DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX) [AID625194, Type: other]Adenosine receptor A [gi:231473]
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35
[SID103770962]
IC50 DRUGMATRIX: Adenosine A1 radioligand binding (ligand: DPCPX) [AID625194, Type: other]Adenosine receptor A [gi:231473]
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36
[SID103770962]
IC50 DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA) [AID625195, Type: other]Adenosine receptor A2 [gi:543740]
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37
[SID103770962]
IC50 DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA) [AID625195, Type: other]Adenosine receptor A2 [gi:543740]
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38
[SID103770962]
IC50 DRUGMATRIX: Adenosine A2A radioligand binding (ligand: AB-MECA) [AID625195, Type: other]Adenosine receptor A2 [gi:543740]
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39
[SID103770962]
IC50 DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA) [AID625196, Type: other]Adenosine receptor A [gi:1351831]
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40
[SID103770962]
IC50 DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA) [AID625196, Type: other]Adenosine receptor A [gi:1351831]
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41
[SID103770962]
IC50 DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin) [AID625200, Type: other]Alpha-1D adrenergic receptor [gi:1168243]
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42
[SID103770962]
IC50 DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin) [AID625200, Type: other]Alpha-1D adrenergic receptor [gi:1168243]
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43
[SID103770962]
IC50 DRUGMATRIX: Alpha-1D adrenergic receptor radioligand binding (ligand: prazosin) [AID625200, Type: other]Alpha-1D adrenergic receptor [gi:1168243]
View
44
[SID103770962]
IC50 DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912) [AID625201, Type: other]Alpha-2A adrenergic receptor [gi:1351829]
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45
[SID103770962]
IC50 DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912) [AID625201, Type: other]Alpha-2A adrenergic receptor [gi:1351829]
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46
[SID103770962]
IC50 DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine) [AID625202, Type: other]Alpha-2B adrenergic receptor [gi:27151763]
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47
[SID103770962]
IC50 DRUGMATRIX: Alpha-2B adrenergic receptor radioligand binding (ligand: Rauwolscine) [AID625202, Type: other]Alpha-2B adrenergic receptor [gi:27151763]
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48
[SID103770962]
IC50 DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912) [AID625203, Type: other]Alpha-2C adrenergic receptor [gi:20141211]
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49
[SID103770962]
IC50 DRUGMATRIX: Adrenergic Alpha-2C radioligand binding (ligand: [3H] MK-912) [AID625203, Type: other]Alpha-2C adrenergic receptor [gi:20141211]
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50
[SID103770962]
IC50 DRUGMATRIX: Adrenergic beta1 radioligand binding (ligand: [125I] Cyanopindolol) [AID625204, Type: other]Beta-1 adrenergic receptor [gi:48429211]
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