Bookmark and Share

BioActivity Data for Compound Nitrovin (CID 13118)

BioActivity Outcomes:
Active(68)
 
 
Inactive(35)
 
 
Inconclusive(37)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
 
NR LBD Fxr(4)
 
 
NR LBD GR(4)
 
 
 
BioAssay Types:
Confirmatory(101)
 
 
 
 
Summary(29)
 
 
 
 
Screening(10)
 
 
 
BioAssay Categories:
Toxicity(6)
 
 
 
Cell-based(23)
 
 
 
BioActivity Types:
Potency(100)
 
 
 
 
IC50(15)
 
 
 
AC50(9)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 140    Data Row: 140   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170466778]
IC50 0.003Colo320 viability from Cell TiterGlo-IC50 [AID1117334, Type: confirmatory]
View
2
[SID170466778]
IC50 0.003HT-29 viability from Cell TiterGlo-IC50 [AID1117330, Type: confirmatory]
View
3
[SID170466778]
IC50 0.0076SW480 viability from Cell TiterGlo-IC50 [AID1117338, Type: confirmatory]
View
4
[SID170466778]
IC50 0.0128RKO viability from Cell TiterGlo-IC50 [AID1117322, Type: confirmatory]
View
5
[SID170466778]
IC50 0.0237GSK3B-pretreated HCT116 viability from Cell TiterGlo-IC50 [AID1117339, Type: confirmatory]
View
6
[SID170466778]
IC50 0.1357HCT116 viability from Cell TiterGlo-IC50 [AID1117332, Type: confirmatory]
View
7
[SID170466778]
IC50 0.372alkaline phosphatase stimulation in WNT3A conditioned C2C12 cells-IC50 [AID1117327, Type: confirmatory]
View
8
[SID170466778]
Ratio Potency (uM) 0.4216qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
View
9
[SID170466778]
Ratio Potency (uM) 0.473043qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
View
10
[SID144206344]
Potency-Replicate_1 0.7498qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
11
[SID170466778]
IC50 1.3539SNU-C1 viability from Cell TiterGlo-IC50 [AID1117323, Type: confirmatory]
View
12
[SID144206344]
Potency-Replicate_1 1.496qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
13
[SID144206344]
Potency-Replicate_1 1.496qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
14
[SID144206344]
Potency-Replicate_1 1.6785qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
View
15
[SID144206344]
Potency-Replicate_1 1.8834qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
16
[SID170466778]
Potency-Replicate_1 2.113qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
View
17
[SID170466778]
Potency-Replicate_1 2.1132qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID1159520, Type: confirmatory]
View
18
[SID144206344]
Potency-Replicate_1 2.371qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
View
19
[SID144206344]
Potency-Replicate_1 2.6603qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
20
[SID144206344]
Potency-Replicate_1 2.6603qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
View