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cyanidin (CID 128861) - Compound BioActivity Data
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BioActivity Outcomes:
Active(17)
 
 
Inactive(5)
 
 
Unspecified(35)
 
 
Top Targets:
Tryp SPc(19)
 
 
 
 
NR LBD LXR(9)
 
 
 
 
Rib hydrolase(2)
 
 
 
AmyAc SI Olig..(1)
 
 
hydroxyacyl-C..(1)
 
 
BioAssay Types:
Literature(54)
 
 
 
 
Screening(1)
 
 
BioActivity Types:
IC50(8)
 
 
 
Kd(3)
 
 
 
EC50(2)
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 57    Data Row: 57   Total Pages: 3   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103574342]
Kd 0.00779Inhibition of human thrombin assessed as equilibrium dissociation constant at 50 to 1000 uM by BIAcore analysis [AID768894, Type: Literature]Prothrombin [gi:135807]
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2
[SID103574342]
IC50 0.25Inhibition of human thrombin amidolytic activity using D-Phe-Pip-Arg-pNA as substrate preincubated for 10 mins followed by substrate addition measured every 12 secs for 10 mins by spectrophotometric analysis [AID768929, Type: Literature]Prothrombin [gi:135807]
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3
[SID103574342]
Ki 2.1Competitive inhibition of Schistosoma mansoni recombinant NAD+ glycohydrolase expressed in Pichia pastoris by Michaelis-Menten equation analysis [AID537631, Type: Literature]
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4
[SID103574342]
Kd 2.2Binding affinity to human LXRalpha-LBD by surface plasmon resonance [AID758943, Type: Literature]Oxysterols receptor LXR-alpha [gi:23503089]
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5
[SID103574342]
IC50 2.3Inhibition of Schistosoma mansoni recombinant NAD+ glycohydrolase expressed in Pichia pastoris by continuous fluorometric method [AID537627, Type: Literature]
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6
[SID103574342]
EC50 3.5Agonist activity at human LXRalpha-LBD assessed as recruitment of co-activator peptide after 2 hrs by TR-FRET assay [AID758940, Type: Literature]Oxysterols receptor LXR-alpha [gi:23503089]
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7
[SID103574342]
IC50 21.8Selectivity ratio of IC50 for human recombinant CD38 to IC50 for Schistosoma mansoni recombinant NAD+ glycohydrolase [AID537629, Type: Literature]
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8
[SID103574342]
IC50 21.8Inhibition of human CD38 using 20 uM 1, N6-etheno NAD+ as substrate by continuous fluorimetric method [AID603318, Type: Literature]ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 [gi:55977782]
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9
[SID103574342]
Competitive inhibition of human thrombin using D-Phe-Pip-Arg-pNA as substrate preincubated for 10 mins followed by substrate addition measured every 12 secs for 10 mins by Lineweaver-Burk plot analysis [AID768892, Type: Literature]Prothrombin [gi:135807]
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10
[SID14720381]
Compound Screen Assay, Human HSD17B4 [AID509, Type: screening]peroxisomal multifunctional enzyme type 2 isoform 2 [Homo sapiens] [gi:4504505]
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11
[SID103574342]
Inhibition of human thrombin assessed as inhibition of fibrinogen gamma-gamma chain formation at 2.5 uM after 5 mins by SDS-PAGE analysis [AID768924, Type: Literature]Prothrombin [gi:135807]
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12
[SID103574342]
Inhibition of human thrombin assessed as inhibition of fibrinogen polymerization at 5 uM preincubated for 10 mins followed by fibrionogen addition measured for 20 mins [AID768926, Type: Literature]Prothrombin [gi:135807]
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13
[SID103574342]
Inhibition of human thrombin assessed as inhibition of fibrinogen alpha-polymer formation at IC50 after 5 mins by SDS-PAGE analysis [AID768914, Type: Literature]Prothrombin [gi:135807]
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14
[SID103574342]
Inhibition of human thrombin assessed as inhibition of fibrinogen gamma-gamma chain formation at IC50 after 5 mins by SDS-PAGE analysis [AID768915, Type: Literature]Prothrombin [gi:135807]
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15
[SID103574342]
Inhibition of human thrombin assessed as inhibition of band decaying corresponding to fibrinogen gamma chains at 2.5 uM after 5 mins by SDS-PAGE analysis [AID768917, Type: Literature]Prothrombin [gi:135807]
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16
[SID103574342]
Inhibition of human thrombin assessed as inhibition of band decaying corresponding to fibrinogen Aalpha chains at 2.5 uM after 5 mins by SDS-PAGE analysis [AID768919, Type: Literature]Prothrombin [gi:135807]
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17
[SID103574342]
Inhibition of human thrombin assessed as inhibition of fibrinogen alpha-polymer formation at 2.5 uM after 5 mins by SDS-PAGE analysis [AID768921, Type: Literature]Prothrombin [gi:135807]
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18
[SID103574342]
Kd 73.2Binding affinity to human LXRbeta-LBD by surface plasmon resonance [AID758944, Type: Literature]Oxysterols receptor LXR-beta [gi:296439251]
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19
[SID103574342]
EC50 125.2Agonist activity at human LXRbeta-LBD assessed as recruitment of co-activator peptide after 2 hrs by TR-FRET assay [AID758939, Type: Literature]Oxysterols receptor LXR-beta [gi:296439251]
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20
[SID103574342]
IC50 60000Inhibition of PGHS2 assessed as conversion of arachidonic acid to prostaglandin [AID378691, Type: Literature]
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