Bookmark and Share
salvinorin A (CID 128563) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(65)
 
 
Inactive(4)
 
 
Inconclusive(11)
 
 
Unspecified(75)
 
 
Top Targets:
7TM GPCR Srx(80)
 
 
 
 
 
7TM GPCR Srsx(2)
 
 
BioAssay Types:
Literature(155)
 
 
 
 
 
BioActivity Types:
Ki(60)
 
 
 
 
EC50(23)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 152    Data Row: 155   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103457931]
EC50 0.0002Agonist activity at kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS binding assay [AID552823, Type: Literature]
View
2
[SID103457931]
Ki 0.00075Displacement of [3H]U69593 from kappa opioid receptor expressed in HEK293 cells [AID552820, Type: Literature]
View
3
[SID103457931]
Ki 0.00075Displacement of [3H]U-69593 from rat cloned KOR [AID290338, Type: Literature]Kappa-type opioid receptor [gi:464313]
View
4
[SID103457931]
Ki 0.0008Displacement of [3H]U69593 from kappa opioid receptor expressed in HEK293 cells by visible spectrophotometry [AID450018, Type: Literature]
View
5
[SID103457931]
EC50 0.00081Agonist activity at human kappa opioid receptor-Galpha-16 fusion protein expressed in CHO cells by calcium flux assay [AID378998, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
6
[SID103457931]
EC50 0.00124Agonist activity at human kappa opioid receptor assessed as inhibition of Galpha-16-induced calcium flux [AID302207, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
7
[SID103457931]
Ki 0.0013Inhibition of [3H]diprenorphine binding to human KOR expressed in CHO cells [AID270608, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
8
[SID103457931]
Ki 0.0013Displacement of [3H]diprenorphine binding from human kappa opioid receptor expressed in CHO cells [AID276331, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
9
[SID103457931]
EC50 0.0018Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding [AID321653, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
10
[SID103457931]
Ki 0.0019Displacement of [125I]IOXY from human recombinant kappa opioid receptor expressed in CHO cells [AID329901, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
11
[SID103457931]
Ki 0.0019Inhibition of [125I]- IOXY binding to human Opioid receptor kappa1 [AID238722, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
12
[SID103457931]
Ki 0.0019Binding affinity to kappa opioid receptor [AID488649, Type: Literature]
View
13
[SID103457931]
Ki 0.0019Displacement of [125]OXY from kappa opioid receptor [AID377277, Type: Literature]
View
14
[SID103457931]
EC50 0.0021Agonist activity at human KOPR expressed in CHO cells assessed as enhancement of [35S]GTPgammaS binding [AID369068, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
15
[SID103457931]
Ki 0.0024Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells [AID321650, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
16
[SID103457931]
Ki 0.0025Displacement of [3H]diprenorphine from human KOPR expressed in CHO cells [AID369067, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
17
[SID103457931]
EC50 0.00282Activity at human kappa opioid receptor expressed in HEK293 cells as intracellular calcium mobilization [AID290339, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
18
[SID103457931]
Ki 0.0029Displacement of [3H]diprenorphine from rat kappa opioid receptor I294A mutant expressed in HEK293 cells [AID317019, Type: Literature]
View
19
[SID103457931]
Ki 0.003Displacement of [3H]diprenorphine from human KOPR expressed in CHO cells [AID640425, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
20
[SID103457931]
Ki 0.00316Displacement of [3H]U69593 from kappa opioid receptor (unknown origin) [AID1063779, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View