2-(4-hydroxy-3,5-dimethylphenyl)-5-methoxy-3-methylindole (CID 128480) - BioAssay Data Summary for Compound
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BioActivity Outcomes:
Active(2)
 
 
Inactive(2)
 
 
Top Targets:
PLAT LOX(1)
 
 
BioActivity Types:
IC50(2)
 
 
SAR
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 4    Data Row: 4   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103279969]
IC50 0.11Inhibitory activity against 5-lipoxygenase in rat neutrophils as inhibition of A 23,187-induced LTB4 production [AID7068, Type: other]Arachidonate 5-lipoxygenase [gi:729945]
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2
[SID103279969]
IC50 0.24Inhibitory activity against 5-lipoxygenase in guinea pig leukocytes was determined [AID6957, Type: other]
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3
[SID103279969]
 In vivo inhibitory activity of histamine induced cutaneous reaction was determined at a conc. of 2.1E-5 mol/ Kg; Not active [AID227429, Type: other]
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4
[SID103279969]
 Inhibitory activity of PAF-induced aggregation was determined on rabbit platelets; Not active at 10e-5 M [AID165621, Type: other]
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