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dibutyldichlorotin (CID 12688) - Compound BioActivity Data
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BioActivity Outcomes:
Active(135)
 
 
Inactive(67)
 
 
Inconclusive(78)
 
 
Unspecified(1)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
 
NR LBD AR(16)
 
 
 
 
NR LBD ER(16)
 
 
 
NR LBD Fxr(10)
 
 
 
NR LBD VDR(10)
 
 
 
 
BioAssay Types:
Confirmatory(214)
 
 
 
 
Summary(48)
 
 
 
 
BioActivity Types:
Potency(191)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 187    Data Row: 281   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144213429]
Potency-Replicate_1 0.0109qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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2
[SID144213429]
TR Potency (uM) 0.0153553qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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3
[SID144213429]
Potency-Replicate_1 0.0172qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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4
[SID144213429]
Potency-Replicate_1 0.0172qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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5
[SID144213429]
Potency-Replicate_1 0.0172qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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6
[SID144213429]
Ratio Potency (uM) 0.0180536qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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7
[SID144213429]
Potency-Replicate_1 0.0245qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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8
[SID144213429]
Ratio Potency (uM) 0.0297324qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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9
[SID144208873]
Ratio Potency (uM) 0.0310121qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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10
[SID144213429]
Potency-Replicate_1 0.0344qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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11
[SID144213429]
Potency-Replicate_1 0.0344qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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12
[SID144213429]
Potency-Replicate_1 0.0344qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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13
[SID144213429]
Potency-Replicate_1 0.0436qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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14
[SID144208873]
Potency-Replicate_1 0.0492qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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15
[SID144213429]
Potency-Replicate_1 0.0549qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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16
[SID144208873]
TR Potency (uM) 0.0551482qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
17
[SID144213429]
Potency-Replicate_1 0.0616qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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18
[SID144213429]
Potency-Replicate_1 0.0776qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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19
[SID144208873]
Ratio Potency (uM) 0.0952428qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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20
[SID144213429]
Potency-Replicate_1 0.123qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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