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N,N-dimethylarginine (CID 123831) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Inactive(137)
 
 
Inconclusive(11)
 
 
Unspecified(10)
 
 
Top Targets:
p450(9)
 
 
 
Amidinotransf(6)
 
 
7TM GPCR Srx(6)
 
 
HSD10-like SD..(4)
 
 
Pyr redox dim(4)
 
 
BioAssay Types:
Confirmatory(132)
 
 
 
Literature(14)
 
 
 
 
 
BioActivity Types:
Potency(111)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 144    Data Row: 159   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103583154]
Km 39Activity at Pseudomonas aeruginosa wild type DDAH1 [AID386446, Type: Literature]
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2
[SID103583154]
Km 170Activity at human recombinant wild type DDAH1 [AID386441, Type: Literature]N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 [gi:6831528]
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3
[SID103583154]
Km 180Activity at rat wild type DDAH1 [AID386444, Type: Literature]N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 [gi:6831527]
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4
[SID103583154]
Km 350Activity at human DDAH1 C275A mutant [AID386442, Type: Literature]
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5
[SID103583154]
Km 810Activity at bovine wild type DDAH1 [AID386445, Type: Literature]N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 [gi:124077407]
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6
[SID103583154]
Ratio of Kcat to Km for rat wild type DDAH1 [AID386449, Type: Literature]N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 [gi:6831527]
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7
[SID103583154]
Ratio of Kcat to Km for bovine wild type DDAH1 [AID386450, Type: Literature]N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 [gi:124077407]
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8
[SID11111070]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
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9
[SID103583154]
Ratio of Kcat to Km for human DDAH1 C275A mutant [AID386448, Type: Literature]
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10
[SID103583154]
Ratio of Kcat to Km for Pseudomonas aeruginosa wild type DDAH1 [AID386451, Type: Literature]
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11
[SID103583154]
Ratio of Kcat to Km for human recombinant wild type DDAH1 [AID386447, Type: Literature]N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 [gi:6831528]
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12
[SID90341201]
Potency 0.2133qHTS screen for enhancers of Arylsulfatase A (ASA1): LOPAC Validation Assay [AID720538, Type: confirmatory]arylsulfatase A [Homo sapiens] [gi:220983390]
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13
[SID90341201]
Potency 1.122qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588453, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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14
[SID90341201]
Potency 4.2284qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). [AID588795, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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15
[SID11111070]
Potency 10qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19 [AID899, Type: confirmatory]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
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16
[SID90341201]
Potency HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Agonists [AID488981, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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17
[SID90341201]
Potency HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Potentiators [AID488982, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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18
[SID90341201]
Potency HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Antagonists [AID488983, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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19
[SID90341201]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: Diaphorase-coupled assay [AID743205, Type: confirmatory]glucokinase isoform 1 [Homo sapiens] [gi:4503951]
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20
[SID90341201]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: ADP-Glo assay [AID743206, Type: confirmatory]glucokinase isoform 1 [Homo sapiens] [gi:4503951]
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21
[SID90341201]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: HTRF assay [AID743207, Type: confirmatory]glucokinase isoform 1 [Homo sapiens] [gi:4503951]
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22
[SID11111070]
Potency qHTS Assay for Modulators of Hemoglobin Beta Chain Splicing [AID925, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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23
[SID90341201]
Potency qHTS Validation Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1) [AID488816, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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24
[SID90341201]
Potency qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]ras-related protein Rab-9A [Homo sapiens] [gi:4759012]
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25
[SID90341201]
Potency Cytometric Cell-Based qHTS for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells [AID2660, Type: confirmatory]serine/threonine-protein kinase mTOR [Homo sapiens] [gi:4826730]
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26
[SID90341201]
Potency High Content Imaging Cell-Based qHTS for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells [AID2666, Type: confirmatory]serine/threonine-protein kinase mTOR [Homo sapiens] [gi:4826730]
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27
[SID90341201]
Potency High Content Imaging Cell-Based qHTS for Inhibitors of the mTORC1 Signaling Pathway in MEF Cells [AID2667, Type: confirmatory]serine/threonine-protein kinase mTOR [Homo sapiens] [gi:4826730]
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28
[SID90341201]
Potency Cytometry Cell-Based qHTS for Inhibitors of the mTORC1 Signaling Pathway in MEF cells [AID2668, Type: confirmatory]serine/threonine-protein kinase mTOR [Homo sapiens] [gi:4826730]
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29
[SID90341201]
Potency qHTS Validation Assay to Find Inhibitors of Pin1 [AID504536, Type: confirmatory]peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [Homo sapiens] [gi:5453898]
View
30
[SID90341201]
Potency qHTS Validation Assay for Iinhibitors of HIV-1 Budding by Blocking the Interaction of PTAP/TSG101 [AID485342, Type: confirmatory]tumor susceptibility gene 101 protein [Homo sapiens] [gi:5454140]
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31
[SID90341201]
Potency qHTS for Inhibitors of Cell Surface uPA Generation: Validation Assay [AID493164, Type: confirmatory]urokinase-type plasminogen activator precursor [Mus musculus] [gi:6679377]
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32
[SID90341201]
Potency qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588456, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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33
[SID90341201]
Potency qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1) [AID488772, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
View
34
[SID90341201]
Potency qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1) [AID488773, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
View
35
[SID11111070]
IkB Signaling [AID445, Type: confirmatory]NF-kappa-B inhibitor alpha [Homo sapiens] [gi:10092619]
View
36
[SID11111070]
Potency qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
37
[SID11111070]
Potency qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
38
[SID11111070]
Cytochrome panel assay with activity outcomes [AID1851_3, Type: other]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
View
39
[SID11111070]
Cytochrome panel assay with activity outcomes [AID1851_5, Type: other]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
View
40
[SID11111070]
Potency qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9 [AID883, Type: confirmatory]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
View
41
[SID11111070]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1 [AID900, Type: confirmatory]caspase-1 isoform alpha precursor [Homo sapiens] [gi:15431328]
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42
[SID11111070]
Potency qHTS Assay for Antagonists of Acetylcholine Muscarinic M1 Receptor: Kinetic Measurement of Intracellular Calcium Response [AID943, Type: confirmatory]muscarinic acetylcholine receptor M1 [Rattus norvegicus] [gi:18249941]
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43
[SID11111070]
Potency qHTS Assay for Antagonists of Acetylcholine Muscarinic M1 Receptor: Measurement of IP-One Response [AID944, Type: confirmatory]muscarinic acetylcholine receptor M1 [Rattus norvegicus] [gi:18249941]
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44
[SID11111070]
Potency qHTS Assay for Anthrax Lethal Toxin Internalization [AID912, Type: confirmatory]lethal factor [Bacillus anthracis str. A2012] [gi:21392848]
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45
[SID90341201]
Potency qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion [AID485298, Type: confirmatory]
View
46
[SID90341201]
Potency qHTS Validation Assay to Find Inhibitors of Chronic Active B-Cell Receptor Signaling [AID485345, Type: confirmatory]
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47
[SID90341201]
Potency Nrf2 qHTS screen for inhibitors: Validation [AID493153, Type: confirmatory] [geneid:4780]
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48
[SID90341201]
Potency qHTS for compounds that reverse cellular toxicity of Amyloid beta (A-beta) peptide in yeast: LOPAC Validation Assay [AID720559, Type: confirmatory]Amyloid beta A4 protein [gi:112927]
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49
[SID11111070]
Potency qHTS Assay for Inhibitors of Firefly Luciferase [AID411, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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50
[SID90341201]
Potency HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Hit Validation in HTRF [AID624455, Type: confirmatory]dopamine D1 receptor [Homo sapiens] [gi:299681]
View