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dehydroacetic acid (CID 122903) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(93)
 
 
Inconclusive(2)
 
 
Unspecified(2)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
NR LBD VDR(4)
 
 
BioAssay Types:
Confirmatory(62)
 
 
 
Summary(24)
 
 
Literature(3)
 
 
 
BioActivity Types:
Potency(80)
 
 
 
IC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 99    Data Row: 99   Total Pages: 5   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103192925]
IC50 1.21Inhibitory concentration against HL60 cells [AID81479, Type: Literature]
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2
[SID74387]
NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
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3
[SID103192925]
IC50 55In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells [AID7096, Type: Literature]
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4
[SID103192925]
IC50 101Inhibitory concentration against Jurkat cells [AID95293, Type: Literature]
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5
[SID144213081]
Potency-Replicate_1 27.306qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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6
[SID144213081]
Potency-Replicate_1 qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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7
[SID144213081]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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8
[SID144213081]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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9
[SID144213081]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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10
[SID144213081]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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11
[SID144213081]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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12
[SID144213081]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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13
[SID144213081]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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14
[SID48413141]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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15
[SID48413141]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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16
[SID48413141]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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17
[SID144213081]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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18
[SID144213081]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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19
[SID144213081]
Ratio Potency (uM) qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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20
[SID144213081]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cells [AID720674, Type: confirmatory]
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