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procyanidin B2 (CID 122738) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Inactive(8)
 
 
Inconclusive(1)
 
 
Unspecified(36)
 
 
BioAssay Types:
Literature(43)
 
 
 
 
BioActivity Types:
IC50(7)
 
 
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 48    Data Row: 48   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103215315]
IC50 9Inhibition of lipid peroxidation in Sprague-Dawley rat heart mitochondria assessed as inhibition of FeSO4-induced malondialdehyde formation [AID398697, Type: Literature]
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2
[SID103215315]
IC50 10.5Antioxidant activity assessed as superoxide radical anion scavenging activity [AID380203, Type: Literature]
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3
[SID103215315]
IC50 11Inhibition of lipid peroxidation in Sprague-Dawley rat heart mitochondria assessed as inhibition of FeSO4-induced oxygen consumption [AID398696, Type: Literature]
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4
[SID103215315]
EC50 25Anti-HIV activity in cell culture assay expressed as EC50 values. [AID81248, Type: other]
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5
[SID103215315]
IC50 25Anti-HIV activity in cell culture assay expressed as IC50 values. [AID81601, Type: other]
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6
[SID103215315]
IC50 58Modulation of classical complement pathway system assessed as hemoglobin release by spectrophotometry [AID380219, Type: Literature]
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7
[SID103215315]
Antimicrobial activity against Staphylococcus aureus after 24 hrs by disk diffusion method [AID336170, Type: Literature]
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8
[SID103215315]
Antimicrobial activity against Candida albicans after 24 hrs by disk diffusion method [AID336171, Type: Literature]
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9
[SID103215315]
Antiviral activity against Potato virus X in half leaf of Chenopodium quinoa at 9.3 mg/mL after 10 days [AID336178, Type: Literature]
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10
[SID103215315]
Inhibition of AMV reverse transcriptase activity assessed as incorporation of dTMP in poly(rA)-oligo(dT) at 0.1 uM [AID400984, Type: Literature]
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11
[SID103215315]
Inhibition of AMV reverse transcriptase activity assessed as incorporation of dTMP in poly(rA)-oligo(dT) at 1 uM [AID400985, Type: Literature]
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12
[SID103215315]
Inhibition of AMV reverse transcriptase activity assessed as incorporation of dTMP in poly(rA)-oligo(dT) at 10 uM [AID400986, Type: Literature]
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13
[SID103215315]
Inhibition of AMV reverse transcriptase activity assessed as incorporation of dTMP in poly(rA)-oligo(dT) at 100 uM [AID400987, Type: Literature]
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14
[SID103215315]
Inhibition of AMV reverse transcriptase activity assessed as incorporation of dTMP in poly(rA)-oligo(dT) at 1000 uM [AID400988, Type: Literature]
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15
[SID103215315]
Inhibition of AMV reverse transcriptase activity assessed as incorporation of dGMP in poly(rC)-oligo(dG) at 0.1 uM [AID400989, Type: Literature]
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16
[SID103215315]
Inhibition of AMV reverse transcriptase activity assessed as incorporation of dGMP in poly(rC)-oligo(dG) at 1 uM [AID400990, Type: Literature]
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17
[SID103215315]
Inhibition of AMV reverse transcriptase activity assessed as incorporation of dGMP in poly(rC)-oligo(dG) at 10 uM [AID400991, Type: Literature]
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18
[SID103215315]
Inhibition of AMV reverse transcriptase activity assessed as incorporation of dGMP in poly(rC)-oligo(dG) at 100 uM [AID400992, Type: Literature]
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19
[SID103215315]
Inhibition of AMV reverse transcriptase activity assessed as incorporation of dGMP in poly(rC)-oligo(dG) at 1000 uM [AID400993, Type: Literature]
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20
[SID103215315]
Binding affinity to bradykinin [AID401340, Type: Literature]
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21
[SID103215315]
Antioxidant activity assessed as trolox equivalent by TEAC assay [AID456317, Type: Literature]
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22
[SID103215315]
Cytotoxicity against human PRMI7951 cells by tetrazolium salt-based colorimetric assay [AID358165, Type: Literature]
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23
[SID103215315]
Cytotoxicity against human KB cells by tetrazolium salt-based colorimetric assay [AID358166, Type: Literature]
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24
[SID103215315]
Cytotoxicity against human A549 cells by tetrazolium salt-based colorimetric assay [AID358167, Type: Literature]
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25
[SID103215315]
Cytotoxicity against human HCT8 cells by tetrazolium salt-based colorimetric assay [AID358168, Type: Literature]
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26
[SID103215315]
Cytotoxicity against human TE671 cells by tetrazolium salt-based colorimetric assay [AID358169, Type: Literature]
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27
[SID103215315]
Cytotoxicity against human MT4 cells by MTT assay [AID380205, Type: Literature]
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28
[SID103215315]
Selectivity index, ratio of CC50 for human MT4 cells to IC50 for HIV infected in human MT4 cells [AID380206, Type: Literature]
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29
[SID103215315]
Antiviral activity against HIV infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect by MTT assay [AID380207, Type: Literature]
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30
[SID103215315]
Antimicrobial activity against Streptococcus pyogenes [AID380211, Type: Literature]
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31
[SID103215315]
Antimicrobial activity against Candida albicans [AID380212, Type: Literature]
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32
[SID103215315]
Antimicrobial activity against Staphylococcus aureus [AID380213, Type: Literature]
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33
[SID103215315]
Antimicrobial activity against Mycobacterium fortuitum [AID380214, Type: Literature]
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34
[SID103215315]
Antimicrobial activity against Enterobacter cloacae [AID380215, Type: Literature]
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35
[SID103215315]
Antimicrobial activity against Salmonella paratyphi [AID380216, Type: Literature]
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36
[SID103215315]
Antimicrobial activity against Pseudomonas aeruginosa [AID380217, Type: Literature]
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37
[SID103215315]
Antimicrobial activity against Escherichia coli [AID380218, Type: Literature]
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38
[SID103215315]
Inhibition against HIV replication in cell culture at 20 ug/mL [AID81794, Type: other]
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39
[SID103215315]
Inhibition against HIV- reverse transcriptase in cell culture at 20 ug/mL [AID82969, Type: other]Reverse transcriptase/RNaseH [gi:82310930]
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40
[SID103215315]
Antiadherent activity against P-fimbriated Escherichia coli in human erythrocyte assessed as suppression of agglutination using latex beads coated with P receptor analogue at 2.4 mg/ml [AID377249, Type: Literature]
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41
[SID103215315]
Antiadherent activity against P-fimbriated Escherichia coli in human erythrocyte assessed as suppression of agglutination using latex beads coated with P receptor analogue at 1.2 mg/ml [AID377250, Type: Literature]
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42
[SID103215315]
Antiadherent activity against P-fimbriated Escherichia coli in human erythrocyte assessed as suppression of agglutination using latex beads coated with P receptor analogue at 0.6 mg/ml [AID377251, Type: Literature]
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43
[SID103215315]
Antiadherent activity against P-fimbriated Escherichia coli in human erythrocyte assessed as suppression of agglutination using latex beads coated with P receptor analogue at 0.3 mg/ml [AID377252, Type: Literature]
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44
[SID103215315]
Antiadherent activity against P-fimbriated Escherichia coli in human erythrocyte assessed as suppression of agglutination using latex beads coated with P receptor analogue at 0.15 mg/ml [AID377253, Type: Literature]
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45
[SID103215315]
IC50 Inhibition of PHA-stimulated human PBMC proliferation assessed as [3H]thymidine uptake after 3 days by scintillation counting [AID338965, Type: Literature]
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46
[SID103215315]
IC50 Modulation of alternative complement pathway system assessed as hemoglobin release by spectrophotometry [AID380220, Type: Literature]
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47
[SID103215315]
Antiviral activity against HSV up to 200 ug/mL by extracellular virucidal assay [AID380204, Type: Literature]
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48
[SID103215315]
Therapeutic index was determined; Not determined [AID235746, Type: other]
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