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Acetylcysteine (CID 12035) - Compound BioActivity Data
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BioActivity Outcomes:
Active(23)
 
 
Inactive(1240)
 
 
Inconclusive(58)
 
 
Unspecified(102)
 
 
Top Targets:
7tm 4(58)
 
 
 
NR LBD PPAR(27)
 
 
 
NR LBD ER(20)
 
 
 
NR LBD AR(16)
 
 
bZIP NFE2-lik..(14)
 
 
 
BioAssay Types:
Confirmatory(584)
 
 
 
 
 
Screening(541)
 
 
 
Literature(212)
 
 
 
 
 
Summary(49)
 
 
 
BioActivity Types:
Potency(553)
 
 
 
 
 
IC50(44)
 
 
 
 
EC50(10)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1081    Data Row: 1423   Total Pages: 72   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56423146]
Potency 10qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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2
[SID855714]
Potency 25.1189qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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3
[SID103182957]
IC50 31Inhibition of horseradish peroxidase [AID295045, Type: Literature]
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4
[SID855714]
Potency 35.4813qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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5
[SID103182957]
Inhibition of 6-hydroxydopamine induced cytotoxicity in rat PC12 cells pretreated for 24 hrs assessed as elevation of intracellular glutathione level [AID360670, Type: Literature]
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6
[SID103182957]
Inhibition of hydrogen peroxide induced cytotoxicity in rat PC12 cells pretreated for 24 hrs assessed as elevation of intracellular glutathione level [AID360671, Type: Literature]
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7
[SID56423146]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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8
[SID103182957]
Reduction of gastrocnemius muscle weight loss in C57BL/6 mouse tail suspension model at 2.5 pmol administered in gastrocnemius muscle qd for 10 days relative to whole body weight [AID527148, Type: Literature]
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9
[SID103182957]
Increase of lipid peroxidation in gastrocnemius muscle of C57BL/6 mouse tail suspension model assessed as decrease of thiobarbituric acid-reactive substance level at 2.5 pmol administered in gastrocnemius muscle qd for 10 days by RT-PCR analysis [AID527151, Type: Literature]
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10
[SID103182957]
Antimicrobial activity against catheter-associated biofilm of methicillin-resistant Staphylococcus aureus [AID285163, Type: Literature]
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11
[SID103182957]
Antimicrobial activity against catheter-associated biofilm of methicillin-resistant Staphylococcus epidermidis [AID285164, Type: Literature]
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12
[SID103182957]
Antimicrobial activity against catheter-associated biofilm of Klebsiella pneumoniae [AID285165, Type: Literature]
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13
[SID103182957]
Inhibition of NO production in BAEC assessed as inhibition of Ca2+ influx at 10 mM [AID513610, Type: Literature]
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14
[SID103182957]
Potentiation of Angeli's salt induced- vasodilatory activity in Sprague-Dawley rat thoracic aorta at 1 mM [AID577800, Type: Literature]
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15
[SID103182957]
Potentiation of 1-Nitrosocyclohexyl trifluoroacetate induced- vasodilatory activity in Sprague-Dawley rat thoracic aorta at 1 mM [AID577801, Type: Literature]
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16
[SID103182957]
FDA HLAED, serum glutamic pyruvic transaminase (SGPT) increase [AID588217, Type: Literature]
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17
[SID103182957]
Inhibition of H2O2-induced cytotoxicity in HUVEC cells assessed as cell viability at 5 mmol/L incubated 4 hrs prior to H2O2 challenge measured after 12 hrs by MTT assay [AID715275, Type: Literature]
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18
[SID103182957]
Inhibition of H2O2-induced cytotoxicity in HUVEC cells assessed as LDH release at 5 mmol/L incubated 4 hrs prior to H2O2 challenge measured after 12 hrs by LDH assay [AID715276, Type: Literature]
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19
[SID103182957]
Antioxidant activity against H2O2-induced lipid accumulation in HUVEC cells assessed as reduction in MDA level at 5 mmol/L incubated 4 hrs prior to H2O2 challenge measured after 12 hrs [AID715277, Type: Literature]
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20
[SID103182957]
Antioxidant activity in HUVEC cells assessed as reduction in H2O2-induced GSH activity at 5 mmol/L incubated 4 hrs prior to H2O2 challenge measured after 12 hrs [AID715278, Type: Literature]
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