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BioActivity Data for Compound DSSTox_CID_31408 (CID 11969781)

BioActivity Outcomes:
Active(18)
 
 
Inactive(25)
 
 
Inconclusive(19)
 
 
Unspecified(1)
 
 
Top Targets:
NR LBD PPAR(6)
 
 
 
 
NR LBD Fxr(4)
 
 
 
 
NR LBD VDR(4)
 
 
 
ACD HspB1 lik..(2)
 
 
NR LBD RXR li..(2)
 
 
BioAssay Types:
Confirmatory(46)
 
 
 
 
 
Summary(14)
 
 
 
 
Screening(3)
 
 
 
BioAssay Categories:
Cell-based(15)
 
 
 
BioActivity Types:
Potency(38)
 
 
 
 
IC50(12)
 
 
 
AC50(6)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 63    Data Row: 63   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170465590]
IC50 0.001RKO viability from Cell TiterGlo-IC50 [AID1117322, Type: confirmatory]
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2
[SID170465590]
IC50 0.001GSK3B-pretreated HCT116 viability from Cell TiterGlo-IC50 [AID1117339, Type: confirmatory]
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3
[SID170465590]
IC50 0.001DLD-1 viability from Cell TiterGlo-IC50 [AID1117352, Type: confirmatory]
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4
[SID170465590]
IC50 0.001SW480 viability from Cell TiterGlo-IC50 [AID1117338, Type: confirmatory]
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5
[SID170465590]
IC50 0.001Colo320 viability from Cell TiterGlo-IC50 [AID1117334, Type: confirmatory]
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6
[SID170465590]
IC50 0.003VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-IC50 [AID1117337, Type: confirmatory]
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7
[SID170465590]
IC50 0.00468Decreased HeLa cell count-IC50 [AID1117347, Type: confirmatory]
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8
[SID170465590]
IC50 0.01176Increased chromatin condensation in HeLa cells-IC50 [AID1117350, Type: confirmatory]
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9
[SID170465590]
IC50 0.0135nuclear beta catenin stimulation in WNT3A conditioned C2C12 cells-IC50 [AID1117325, Type: confirmatory]
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10
[SID170465590]
IC50 0.04422VEGF stimulated ADSC/ECFC co-culture nuclear area decrease (viability)-IC50 [AID1117324, Type: confirmatory]
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11
[SID170465590]
Potency-Replicate_1 0.1333qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID1159520, Type: confirmatory]
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12
[SID170465590]
Potency-Replicate_1 0.2985qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID1159521, Type: confirmatory]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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13
[SID170465590]
Potency-Replicate_1 0.9521qHTS assay to identify small molecule agonists of the endoplasmic reticulum stress response signaling pathway - cell viability counter screen [AID1159517, Type: confirmatory]
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14
[SID170465590]
Potency-Replicate_1 9.4384qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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15
[SID170465590]
Ac50 31.6228qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel [AID1117312, Type: confirmatory]
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16
[SID170465590]
nuclear beta catenin stimulation in WNT3A conditioned C2C12 cells-screen [AID1117326, Type: screening]
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17
[SID170465590]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743226, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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18
[SID170465590]
qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743240, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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19
[SID170465590]
AC50 (uM) 39.8107qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 blue channel [AID1117304, Type: confirmatory]
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20
[SID170465590]
IC50 10Increased HeLa cells with 4N DNA content-IC50 [AID1117351, Type: confirmatory]
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