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valdecoxib (CID 119607) - Compound BioActivity Data
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BioActivity Outcomes:
Active(117)
 
 
Inactive(896)
 
 
Inconclusive(25)
 
 
Unspecified(381)
 
 
Top Targets:
alpha CA I II..(48)
 
 
 
7TM GPCR Srx(40)
 
 
 
7TM GPCR Srsx(34)
 
 
 
prostaglandin..(20)
 
 
 
NR LBD PPAR(14)
 
 
 
BioAssay Types:
Screening(464)
 
 
 
 
Confirmatory(454)
 
 
 
 
 
Literature(268)
 
 
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(290)
 
 
 
 
 
IC50(187)
 
 
 
 
Ki(105)
 
 
 
 
EC50(16)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1232    Data Row: 1419   Total Pages: 71   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103225393]
IC50 0.005Compound was tested for its inhibitory activity against recombinant human Prostaglandin G/H synthase 2 [AID162347, Type: Literature]
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2
[SID103225393]
IC50 0.005In Vitro activity of compound against human recombinant Prostaglandin G/H synthase 2 [AID162482, Type: Literature]
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3
[SID103225393]
IC50 0.005Inhibitory activity against human recombinant cyclooxygenase 2 [AID254750, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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4
[SID103225393]
IC50 0.00501Inhibition of human Prostaglandin G/H synthase 2 [AID160434, Type: Literature]
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5
[SID103225393]
Ki 0.0053Inhibition of Sulfurihydrogenibium yellowstonense YO3AOP1 recombinant carbonic anhydrase preincubated for 15 mins by CO2 hydration stopped-flow assay [AID743512, Type: Literature]
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6
[SID103225393]
Ki 0.013Inhibitory activity against cloned human CA12 [AID258733, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
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7
[SID103225393]
Ki 0.013Inhibition of human carbonic anhydrase 12-catalyzed CO2 hydration activity by stopped flow assay [AID620688, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
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8
[SID103225393]
Ki 0.013Inhibition of human membrane bound carbonic anhydrase 12 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydration assay [AID770582, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
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9
[SID103225393]
Ki 0.013Inhibition of human recombinant CA12 catalytic domain pre-incubated for 15 mins by stopped-flow CO2 hydration method [AID711038, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
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10
[SID103225393]
Ki 0.019Inhibition of Brucella suis carbonic anhydrase I by spectrophotometry at pH 8.3 [AID577531, Type: Literature]
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11
[SID103225393]
IC50 0.027Inhibitory activity against human carbonic anhydrase IX was determined [AID48294, Type: Literature]
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12
[SID103225393]
Ki 0.027Inhibitory activity against human carbonic anhydrase IX (hCA IX) by using CO2 hydrase assay method [AID48303, Type: Literature]
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13
[SID103225393]
Ki 0.027Inhibition of human recombinant carbonic anhydrase 9 catalytic domain by stopped flow CO2 hydrase assay [AID369274, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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14
[SID103225393]
Ki 0.027Inhibitory activity against cloned human CA9 [AID258732, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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15
[SID103225393]
Ki 0.027Inhibition of human carbonic anhydrase 9-catalyzed CO2 hydration activity by stopped flow assay [AID620687, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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16
[SID103225393]
Ki 0.027Inhibition of human recombinant CA9 catalytic domain pre-incubated for 15 mins by stopped-flow CO2 hydration method [AID711037, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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17
[SID103225393]
Ki 0.027Inhibition of human membrane bound carbonic anhydrase 9 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydration assay [AID770583, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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18
[SID103225393]
Ki 0.0287Inhibition of cloned Stylophora pistillata alpha-CA expressed in human HEK293 cells by stopped-flow CO2 assay [AID436565, Type: Literature]
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19
[SID103225393]
Ki 0.0287Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assay [AID552130, Type: Literature]
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20
[SID103225393]
IC50 0.04Inhibition of human recombinant COX2 [AID312221, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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