Bookmark and Share
Lopac0_000443 (CID 11957530) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(7)
 
 
Inactive(132)
 
 
Inconclusive(11)
 
 
Top Targets:
NR LBD RAR(6)
 
 
NR LBD COUP-T..(5)
 
 
7tm 4(5)
 
 
NR LBD RXR li..(4)
 
 
 
PIKKc TOR(4)
 
 
BioAssay Types:
Screening(79)
 
 
 
Confirmatory(66)
 
 
 
 
Literature(3)
 
 
 
BioActivity Types:
Potency(66)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 77    Data Row: 150   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID90341550]
Potency 20.5878qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
View
2
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277, Type: screening]
View
3
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_57, Type: screening]retinoic acid receptor RXR-alpha isoform a [Homo sapiens] [gi:4506755]
View
4
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_38, Type: screening]nuclear receptor subfamily 5 group A member 2 isoform 2 [Homo sapiens] [gi:4504343]
View
5
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_52, Type: screening]nuclear receptor ROR-alpha isoform c [Homo sapiens] [gi:4506577]
View
6
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_2, Type: screening]estrogen receptor isoform 1 [Homo sapiens] [gi:62821794]
View
7
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_1, Type: screening]AR protein [Homo sapiens] [gi:124375976]
View
8
[SID90341550]
Potency 10.3225qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion [AID485298, Type: confirmatory]
View
9
[SID90341550]
Potency 18.3489Validation screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID493106, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
View
10
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_14, Type: screening]oxysterols receptor LXR-beta isoform 1 [Homo sapiens] [gi:85362735]
View
11
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_44, Type: screening]peroxisome proliferator-activated receptor gamma isoform 1 [Homo sapiens] [gi:116284368]
View
12
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_45, Type: screening]peroxisome proliferator-activated receptor gamma isoform 1 [Homo sapiens] [gi:116284368]
View
13
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_18, Type: screening]nuclear receptor subfamily 1 group I member 3 isoform 12 [Homo sapiens] [gi:117938738]
View
14
[SID90341550]
Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign [AID504810, Type: Literature]TSHR protein [Homo sapiens] [gi:118341367]
View
15
[SID90341550]
Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign [AID504812, Type: Literature]TSHR protein [Homo sapiens] [gi:118341367]
View
16
[SID163564397]
Fluorescence polarization based primary biochemical high throughput screening assay of LOPAC1280 to identify inhibitors of hepatitis C non-structural protein 3 helicase [AID687035, Type: screening]NS3, partial [Hepatitis C virus] [gi:125541954]
View
17
[SID90341550]
Potency qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
View
18
[SID17405006]
HTS for Tumor Hsp90 Inhibitors [AID429, Type: screening]heat shock protein HSP 90-alpha isoform 2 [Homo sapiens] [gi:154146191]
View
19
[SID90341550]
Potency qHTS Validation Assay to Find Inhibitors of Phosphoglycerate Mutase [AID504548, Type: confirmatory]2,3-bisphosphoglycerate-independent phosphoglycerate mutase [Leishmania major strain Friedlin] [gi:157877932]
View
20
[SID17405006]
HTS for small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress [AID2732, Type: screening]DNA damage-inducible transcript 3 protein [Mus musculus] [gi:160707929]
View