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BioActivity Data for Compound Lopac0_000443 (CID 11957530)

BioActivity Outcomes:
Active(7)
 
 
Inactive(132)
 
 
Inconclusive(11)
 
 
Top Targets:
NR LBD RAR(6)
 
 
7tm 4(5)
 
 
NR LBD COUP-T..(5)
 
 
Pyr redox dim(4)
 
 
 
PIKKc TOR(4)
 
 
BioAssay Types:
Screening(79)
 
 
 
Confirmatory(66)
 
 
 
 
Literature(3)
 
 
 
BioActivity Types:
Potency(66)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 77    Data Row: 150   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID90341550]
Potency 20.5878qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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2
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_38, Type: screening]nuclear receptor subfamily 5 group A member 2 isoform 2 [Homo sapiens] [gi:4504343]
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3
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_52, Type: screening]nuclear receptor ROR-alpha isoform c [Homo sapiens] [gi:4506577]
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4
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_57, Type: screening]retinoic acid receptor RXR-alpha isoform a [Homo sapiens] [gi:4506755]
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5
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_2, Type: screening]estrogen receptor isoform 1 [Homo sapiens] [gi:62821794]
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6
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_1, Type: screening]AR protein [Homo sapiens] [gi:124375976]
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7
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277, Type: screening]
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8
[SID90341550]
Potency 10.3225qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion [AID485298, Type: confirmatory]
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9
[SID90341550]
Potency 18.3489Validation screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID493106, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
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10
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_14, Type: screening]oxysterols receptor LXR-beta isoform 1 [Homo sapiens] [gi:85362735]
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11
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_44, Type: screening]peroxisome proliferator-activated receptor gamma isoform 1 [Homo sapiens] [gi:116284368]
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12
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_45, Type: screening]peroxisome proliferator-activated receptor gamma isoform 1 [Homo sapiens] [gi:116284368]
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13
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_18, Type: screening]nuclear receptor subfamily 1 group I member 3 isoform 12 [Homo sapiens] [gi:117938738]
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14
[SID90341550]
Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign [AID504810, Type: Literature]TSHR protein [Homo sapiens] [gi:118341367]
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15
[SID90341550]
Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign [AID504812, Type: Literature]TSHR protein [Homo sapiens] [gi:118341367]
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16
[SID90341550]
Potency Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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17
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_29, Type: screening]glucocorticoid receptor isoform gamma [Homo sapiens] [gi:66528677]
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18
[SID17405006]
HTS for BAP1 Enzyme inhibitors [AID436, Type: screening]Ubiquitin carboxyl-terminal hydrolase BAP1 [gi:68565074]
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19
[SID90341550]
Potency qHTS for Inhibitors of Glutaminase (GLS): LOPAC Validation [AID624146, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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20
[SID87219223]
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors. [AID2277_7, Type: screening]hepatocyte nuclear factor 4-alpha isoform HNF4alpha7 [Homo sapiens] [gi:71725341]
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