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Lopac0_000420 (CID 11957527) - Compound BioActivity Data
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BioActivity Outcomes:
Active(26)
 
 
Inactive(129)
 
 
Inconclusive(23)
 
 
Unspecified(2)
 
 
Top Targets:
Pyr redox dim(7)
 
 
 
7tm 4(6)
 
 
ANK(5)
 
 
 
HELICc(4)
 
 
PIKKc TOR(4)
 
 
 
BioAssay Types:
Confirmatory(158)
 
 
 
 
 
Screening(14)
 
 
 
Literature(5)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(158)
 
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 155    Data Row: 180   Total Pages: 9   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID124891647]
Potency 0.1122qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID124891647]
Potency 0.1585qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID50106196]
Potency 1.4125qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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4
[SID50106195]
Potency 1.4125qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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5
[SID90341174]
Potency 2.5918qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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6
[SID50106195]
Potency 2.8184qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 3D7 [AID1876, Type: confirmatory]
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7
[SID50106195]
Potency 3.2944Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID488745, Type: confirmatory]
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8
[SID50106195]
Potency 3.9811qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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9
[SID50106195]
Potency 3.9811qHTS for differential inhibitors of proliferation of Plasmodium falciparum line W2 [AID1883, Type: confirmatory]
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10
[SID50106195]
Potency 3.9811Validation screen for inhibitors of Lassa infection [AID463096, Type: confirmatory]
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11
[SID50106195]
Potency 4.4668qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 7G8 [AID1815, Type: confirmatory]
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12
[SID50106195]
Potency 4.4668qHTS for differential inhibitors of proliferation of Plasmodium falciparum line GB4 [AID1816, Type: confirmatory]
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13
[SID50106195]
Potency 4.6535Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID488752, Type: confirmatory]
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14
[SID50106195]
Potency 5.0119qHTS for differential inhibitors of proliferation of Plasmodium falciparum line D10 [AID1877, Type: confirmatory]
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15
[SID90341174]
Potency 5.0119qHTS for Inhibitors of ATXN expression: Validation [AID588378, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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16
[SID50106195]
Potency 5.6234qHTS for differential inhibitors of proliferation of Plasmodium falciparum line HB3 [AID1886, Type: confirmatory]
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17
[SID50106195]
Potency 5.9728qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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18
[SID50106195]
Potency 6.3096qHTS for differential inhibitors of proliferation of Plasmodium falciparum line Dd2 [AID1882, Type: confirmatory]
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19
[SID50106195]
Potency 10qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2353, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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20
[SID50106195]
Potency 19.9526qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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