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MLS000522697 (CID 11957178) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(306)
 
 
Inconclusive(4)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(17)
 
 
alkPPc(8)
 
 
Bcl-2 like(8)
 
 
G-alpha(7)
 
 
 
 
PTPc(5)
 
 
BioAssay Types:
Screening(175)
 
 
 
 
 
Confirmatory(123)
 
 
 
 
Literature(4)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(76)
 
 
 
 
IC50(34)
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 292    Data Row: 317   Total Pages: 16   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17401853]
Potency 8.2753Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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2
[SID17401853]
Potency 19.9526qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
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3
[SID17401853]
Profiling compound fluorescence on Avidin Beads with 488 nm excitation and 530 nm emission [AID1775, Type: other]
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4
[SID17401853]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. [AID1439, Type: screening]guanine nucleotide-binding protein G(o) subunit alpha isoform a [Homo sapiens] [gi:10567816]
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5
[SID17401853]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions. [AID1504, Type: summary]GNAO1 protein [Homo sapiens] [gi:34190601]
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6
[SID17401853]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. [AID1439, Type: screening]RGS7, partial [Homo sapiens] [gi:1166512]
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7
[SID17401853]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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8
[SID17401853]
Potency 2.8184qHTS Assay for Inhibitors of Influenza NS1 Protein Function [AID2326, Type: confirmatory]nonstructural protein 1 [Influenza A virus (A/WSN/1933(H1N1))] [gi:194352380]
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9
[SID17401853]
Potency qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor [AID492947, Type: confirmatory]beta-2 adrenergic receptor [Homo sapiens] [gi:4501969]
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10
[SID17401853]
Factor XIa 1536 HTS [AID798, Type: screening]coagulation factor XI [Homo sapiens] [gi:180352]
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11
[SID17401853]
IC50_Mean High Throughput Imaging Assay for Beta-Catenin [AID1665, Type: confirmatory]catenin beta-1 [Homo sapiens] [gi:4503131]
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12
[SID17401853]
uHTS for the identification of compounds that potentiate TRAIL-induced apoptosis of cancer cells [AID1443, Type: screening]tumor necrosis factor ligand superfamily member 10 isoform 1 [Homo sapiens] [gi:4507593]
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13
[SID17401853]
Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) [AID1032, Type: screening]NCOA2 protein [Homo sapiens] [gi:62201602]
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14
[SID17401853]
Measurement of TR-FRET detection format artefact in the screen for agonists of steroid receptor coactivator 2 (SRC-2) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) [AID1049, Type: other]NCOA2 protein [Homo sapiens] [gi:62201602]
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15
[SID17401853]
Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign [AID504810, Type: Literature]TSHR protein [Homo sapiens] [gi:118341367]
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16
[SID17401853]
Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign [AID504812, Type: Literature]TSHR protein [Homo sapiens] [gi:118341367]
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17
[SID17401853]
Primary cell-based high throughput assay for inhibitors of the Janus kinase 2 mutant JAK2V617F [AID1446, Type: screening]Janus kinase 2 (a protein tyrosine kinase) [Homo sapiens] [gi:119579178]
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18
[SID17401853]
Kallikrein 5 1536 HTS [AID873, Type: screening]kallikrein-5 preproprotein [Homo sapiens] [gi:6912644]
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19
[SID17401853]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD2 [AID1566, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 isoform 1 [Homo sapiens] [gi:11545912]
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20
[SID17401853]
Potency qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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