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isopentenyl pyrophosphate (CID 1195) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Unspecified(12)
 
 
BioAssay Types:
Literature(17)
 
 
 
BioActivity Types:
EC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 17    Data Row: 17   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103388476]
EC50 1.02Mean effective concentration of compound was determined in stimulating Vgamma9 / Vdelta2 T cell [AID216550, Type: Literature]
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2
[SID103388476]
EC50 3.16Effective concentration to activate gammadelta T cells [AID221770, Type: Literature]
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3
[SID103388476]
EC50 5.9Immunostimulatory activity in human Vgamma9/Vdelta2 T cells assessed as TNFalpha production after 12 hrs by ELISA [AID375408, Type: Literature]
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4
[SID103388476]
EC50 10Effective concentration range of compound was determined in stimulating Vgamma9 / Vdelta2 T cell [AID216549, Type: Literature]
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5
[SID103388476]
Stimulation of human Vgamma9Vdelta2 T lymphocytes assessed as gamma delta expansion factor after 7 days [AID390270, Type: Literature]
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6
[SID103388476]
EC50 81.076Agonist activity at human Vgamma9Vdelta2 receptor expressed in T cells assessed as stimulation of TNFalpha release by ELISA [AID317317, Type: Literature]
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7
[SID103388476]
Stability in presence of alkaline phosphatase [AID375409, Type: Literature]
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8
[SID103388476]
Stability in presence alkaline phosphatase after 20 mins by HPLC-MS analysis [AID375410, Type: Literature]
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9
[SID103388476]
Stability in presence alkaline phosphatase after 30 mins by HPLC-MS analysis [AID375411, Type: Literature]
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10
[SID103388476]
Stability in presence alkaline phosphatase after 60 mins by HPLC-MS analysis [AID375412, Type: Literature]
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11
[SID103388476]
Relative yield of the product (FPP) derived from the compound with DMAPP in the enzymatic reaction catalyzed by FPP synthase from avian liver [AID38009, Type: Literature]
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12
[SID103388476]
Relative yield of the product (FPP) derived from the compound with GPP in the enzymatic reaction catalyzed by FPP synthase from avian liver [AID38010, Type: Literature]
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13
[SID103388476]
Relative yield of the product (FPP) derived from the compound with DMAPP in the enzymatic reaction catalyzed by FPP synthase from Bacillus stearothermophilus [AID40492, Type: Literature]
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14
[SID103388476]
Relative yield of the product (FPP) derived from the compound with GPP in the enzymatic reaction catalyzed by FPP synthase from Bacillus stearothermophilus [AID40493, Type: Literature]
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15
[SID103388476]
Relative yield of the product (FPP) derived from the compound with DMAPP in the enzymatic reaction catalyzed by FPP synthase from porcine liver [AID159562, Type: Literature]
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16
[SID103388476]
Relative yield of the product (FPP) derived from the compound with GPP in the enzymatic reaction catalyzed by FPP synthase from porcine liver [AID159563, Type: Literature]
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17
[SID103388476]
Activity against isopentenyl pyrophosphate (IPP) in Vgamma9 / Vdelta2 T cell [AID216548, Type: Literature]
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