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MLS000540213 (CID 11948768) - Compound BioActivity Data
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BioActivity Outcomes:
Active(26)
 
 
Inactive(695)
 
 
Inconclusive(14)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
 
7TM GPCR Srsx(19)
 
 
alkPPc(12)
 
 
Bcl-2 like(11)
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(495)
 
 
 
 
 
Confirmatory(219)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(149)
 
 
 
 
 
IC50(44)
 
 
 
 
EC50(20)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 671    Data Row: 737   Total Pages: 37   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17386252]
Potency 1.4125qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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2
[SID17386252]
EC50 6.133Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity [AID1902, Type: confirmatory]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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3
[SID17386252]
EC50 6.986Luminescence Microorganism-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to SK(-)GAS Group A Streptococcus [AID1900, Type: confirmatory]
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4
[SID17386252]
IC50 10.677High Throughput Screen to Identify Inhibitors of Mycobacterium tuberculosis H37Rv [AID1626, Type: confirmatory]
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5
[SID17386252]
IC50_Artemis_Mean 16.4Dose Response confirmation of small molecule inhibitors originally identified via uHTS of Artemis endonuclease activity via a fluorescence intensity assay [AID720701, Type: confirmatory]protein artemis isoform a [Homo sapiens] [gi:76496497]
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6
[SID17386252]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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7
[SID17386252]
HCS assay for microtubule stabilizers [AID2205, Type: screening]tubulin beta chain isoform b [Homo sapiens] [gi:29788785]
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8
[SID17386252]
uHTS identification of inhibitors of NadD in a Colorimetric assay [AID602399, Type: screening]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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9
[SID17386252]
Modulators of the EP2 prostaglandin E2 receptor - Primary Screening [AID940, Type: screening]prostaglandin E2 receptor EP2 subtype [Homo sapiens] [gi:31881630]
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10
[SID17386252]
Leishmania major promastigote HTS [AID1063, Type: screening]
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11
[SID17386252]
Antagonist of Human D 1 Dopamine Receptor: qHTS [AID504652, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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12
[SID17386252]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of human platelet activating factor acetylhydrolase 2 (PAFAH2) [AID492956, Type: screening]platelet-activating factor acetylhydrolase 2, cytoplasmic [Homo sapiens] [gi:4758878]
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13
[SID17386252]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype [AID757, Type: screening]Rac1 protein [Homo sapiens] [gi:8574038]
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14
[SID17386252]
Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR) [AID2796, Type: screening]aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003]
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15
[SID17386252]
Primary cell-based screen for identification of compounds that inhibit the two-pore domain potassium channel KCNK9 [AID488922, Type: screening]potassium channel subfamily K member 9 [Homo sapiens] [gi:7706135]
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16
[SID17386252]
Confirmatory screen for identification of compounds that inhibit the two-pore domain potassium channel (KCNK9) [AID492992, Type: screening]potassium channel subfamily K member 9 [Homo sapiens] [gi:7706135]
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17
[SID17386252]
MLPCN Streptokinase Expression Inhibition [AID1662, Type: screening]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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18
[SID17386252]
HTS for small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress [AID2732, Type: screening]DNA damage-inducible transcript 3 protein [Mus musculus] [gi:160707929]
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19
[SID17386252]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of the prolyl oligopeptidase-like enzyme (PREPL) [AID2751, Type: screening]Prolyl endopeptidase-like [Homo sapiens] [gi:153217451]
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20
[SID17386252]
Fluorescence polarization-based biochemical high throughput confirmation assay to identify inhibitors of the prolyl oligopeptidase-like enzyme (PREPL) [AID2803, Type: screening]Prolyl endopeptidase-like [Homo sapiens] [gi:153217451]
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