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matairesinol (CID 119205) - Compound BioActivity Data
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BioActivity Outcomes:
Active(11)
 
 
Inactive(16)
 
 
Unspecified(8)
 
 
Top Targets:
LamG(2)
 
 
 
Myc N(1)
 
 
STAT bind(1)
 
 
P53(1)
 
 
PTZ00435(1)
 
 
BioAssay Types:
Literature(25)
 
 
 
 
Screening(10)
 
 
BioActivity Types:
IC50(9)
 
 
 
Kd(1)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 34    Data Row: 35   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103436031]
Kd 0.30903Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin [AID318680, Type: Literature]Sex hormone-binding globulin [gi:134907]
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2
[SID103436031]
EC50 2Antiviral activity against HIV1 in human H9 cells assessed as inhibition of viral replication [AID357033, Type: Literature]
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3
[SID103436031]
IC50 5Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs [AID436320, Type: Literature]
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4
[SID103436031]
IC50 21.9Cytotoxicity against human H9 cells [AID357032, Type: Literature]
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5
[SID103436031]
IC50 23.65Anticancer activity against human XF498 cells by SRB assay [AID591310, Type: Literature]
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6
[SID103436031]
IC50 23.8Anticancer activity against human A549 cells by SRB assay [AID591308, Type: Literature]
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7
[SID103436031]
Induction of apoptosis in human EBV deficient BL41 cells assessed as condensed and fragmented nuclei at 25 to 100 uM after 18 hrs by epifluorescent microscopy [AID426070, Type: Literature]
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8
[SID103436031]
Induction of apoptosis in human E2R cells expressing EBV assessed as condensed and fragmented nuclei at 25 to 100 uM after 18 hrs by epifluorescent microscopy [AID426071, Type: Literature]
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9
[SID103436031]
Antioxidant activity in human E2R cells assessed as intracellular peroxide level at 25 to 100 uM after 1 hr by flow cytometry in presence of DCFH-DA [AID426072, Type: Literature]
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10
[SID103436031]
Antioxidant activity assessed as DPPH radical scavenging activity [AID333834, Type: Literature]
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11
[SID103436031]
Antioxidant activity assessed as AAPH radical scavenging activity after 3 hrs [AID333835, Type: Literature]
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12
[SID103436031]
IC50 30Anticancer activity against human SK-MEL-2 cells by SRB assay [AID591309, Type: Literature]
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13
[SID103436031]
IC50 30Anticancer activity against human SKOV3 cells by SRB assay [AID591307, Type: Literature]
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14
[SID103436031]
IC50 52Displacement of [3H]DHT from human serum SHBG [AID399375, Type: Literature]Sex hormone-binding globulin [gi:134907]
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15
[SID103436031]
IC50 94.53Antiinflammatory activity in mouse BV2 cells assessed as inhibition of lipopolysaccharide induced NO production [AID591311, Type: Literature]
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16
[SID103436031]
IC50 100Inhibition of Streptococcus mutans OMZ65 recombinant sortase A delta-40 mutant using Dabcyl-QALPETGEE-Edans as substrate after 1 hr by fluorescence spectrophotometry [AID1062030, Type: Literature]
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17
[SID103436031]
Inhibitory activity against 3'-processing by HIV-1 Integrase at 100 uM [AID91438, Type: Literature]Integrase [gi:82312013]
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18
[SID103436031]
Inhibitory activity against strand transfer by HIV-1 Integrase at 100 uM [AID91560, Type: Literature]Integrase [gi:82312013]
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19
[SID103436031]
Therapeutic index, ratio of IC50 for human H9 cells to EC50 for HIV1 [AID357034, Type: Literature]
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20
[SID85843799]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of the Sonic Hedgehog Signaling Pathway [AID2313, Type: screening]
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