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gamma-Aminobutyric Acid (CID 119) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(247)
 
 
Inactive(1284)
 
 
Inconclusive(80)
 
 
Unspecified(220)
 
 
Top Targets:
Neur chan LBD(168)
 
 
 
 
Neur chan mem..(58)
 
 
 
 
7TM GPCR Srx(30)
 
 
 
7TM GPCR Srsx(24)
 
 
PBP1 GABAb re..(17)
 
 
 
BioAssay Types:
Confirmatory(629)
 
 
 
 
 
Literature(544)
 
 
 
 
 
Screening(536)
 
 
 
 
Summary(16)
 
 
BioActivity Types:
Potency(533)
 
 
 
 
 
IC50(208)
 
 
 
 
 
EC50(72)
 
 
 
 
Ki(21)
 
 
 
AC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1221    Data Row: 1831   Total Pages: 37   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-2 [gi:120758]
View
2
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-3 [gi:120761]
View
3
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-4 [gi:120763]
View
4
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-5 [gi:120764]
View
5
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-1 [gi:120769]
View
6
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-1 [gi:120782]
View
7
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-2 [gi:120788]
View
8
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-3 [gi:120790]
View
9
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-6 [gi:232127]
View
10
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit delta [gi:544363]
View
11
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit pi [gi:3023821]
View
12
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit epsilon [gi:13959374]
View
13
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-1 [gi:51317298]
View
14
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-3 [gi:52000955]
View
15
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-2 [gi:52000957]
View
16
[SID103173784]
IC50 0.013Inhibition of [3H]GABA binding in GABAA receptor in rat brain synaptic membranes [AID267285, Type: Literature]GABA theta subunit [gi:81902501]
View
17
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]GABA theta subunit [gi:81902501]
View
18
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-3 [gi:52000955]
View
19
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-1 [gi:51317298]
View
20
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-2 [gi:52000957]
View
21
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit epsilon [gi:13959374]
View
22
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit pi [gi:3023821]
View
23
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit delta [gi:544363]
View
24
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-6 [gi:232127]
View
25
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-3 [gi:120790]
View
26
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-2 [gi:120788]
View
27
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-1 [gi:120782]
View
28
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-1 [gi:120769]
View
29
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-5 [gi:120764]
View
30
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-3 [gi:120761]
View
31
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-4 [gi:120763]
View
32
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat spinal cord [AID270052, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-2 [gi:120758]
View
33
[SID103173784]
IC50 0.015Displacement of [3H]muscimol from GABAA receptor in Sprague-Dawley rat spinal cord brainstem membranes [AID286350, Type: Literature]
View
34
[SID103173784]
IC50 0.015In vitro inhibition of [3H]THIP binding to Gamma-aminobutyric acid receptor in rat brain synaptic membranes [AID71437, Type: Literature]
View
35
[SID103173784]
IC50 0.017Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortex [AID71401, Type: Literature]Gamma-aminobutyric acid type B receptor subunit 1 [gi:12643494]
View
36
[SID103173784]
IC50 0.017Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortex [AID71401, Type: Literature]Gamma-aminobutyric acid type B receptor subunit 2 [gi:12643481]
View
37
[SID103173784]
IC50 0.018Binding affinity against Gamma-aminobutyric acid A receptor in rat cerebral cortex [AID71822, Type: Literature]
View
38
[SID103173784]
IC50 0.02Displacement of [3H]gamma-aminobutyric acid from sodium-independent Gamma-aminobutyric acid (GABA-A) receptor synaptic membrane binding sites from rat brain tissue [AID71429, Type: Literature]
View
39
[SID103173784]
IC50 0.022Inhibitory effect was measured for [3H]GABA-uptake from rat synaptosomal membrane [AID71443, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-2 [gi:120758]
View
40
[SID103173784]
IC50 0.024Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat cerebral cortex [AID270053, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-2 [gi:120758]
View
41
[SID103173784]
IC50 0.024Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat cerebral cortex [AID270053, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-3 [gi:120761]
View
42
[SID103173784]
IC50 0.024Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat cerebral cortex [AID270053, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-4 [gi:120763]
View
43
[SID103173784]
IC50 0.024Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat cerebral cortex [AID270053, Type: Literature]Gamma-aminobutyric acid receptor subunit beta-1 [gi:120769]
View
44
[SID103173784]
IC50 0.024Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat cerebral cortex [AID270053, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-1 [gi:120782]
View
45
[SID103173784]
IC50 0.024Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat cerebral cortex [AID270053, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-2 [gi:120788]
View
46
[SID103173784]
IC50 0.024Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat cerebral cortex [AID270053, Type: Literature]Gamma-aminobutyric acid receptor subunit alpha-5 [gi:120764]
View
47
[SID103173784]
IC50 0.024Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat cerebral cortex [AID270053, Type: Literature]Gamma-aminobutyric acid receptor subunit gamma-3 [gi:120790]
View
48
[SID103173784]
IC50 0.024Displacement of [3H]muscimol from GABAA receptor in Sprague-Dawley rat cerebral cortex membranes [AID286351, Type: Literature]
View
49
[SID103173784]
IC50 0.024Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat cerebral cortex [AID270053, Type: Literature]Gamma-aminobutyric acid receptor subunit pi [gi:3023821]
View
50
[SID103173784]
IC50 0.024Displacement of [3H]muscimol from GABA-A receptor in Sprague-Dawley rat cerebral cortex [AID270053, Type: Literature]Gamma-aminobutyric acid receptor subunit epsilon [gi:13959374]
View