CHEMBL211296 (CID 11846315) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(8)
 
 
Top Targets:
HATPase c(6)
 
 
BioAssay Types:
Literature(8)
 
 
BioActivity Types:
EC50(6)
 
 
SAR
Target summary
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 8   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103494091]
EC50 0.066Inhibition of BODIPY-AG binding to human HSP90 [AID266546, Type: Literature]Heat shock protein HSP 90-beta [gi:17865718]
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2
[SID103494091]
EC50 0.072Inhibition of BODIPY-AG binding to dog Grp94 [AID266547, Type: Literature]Endoplasmin [gi:729425]
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3
[SID103494091]
EC50 0.14Upregulation of Hsp70 in SKBR3 cells [AID266552, Type: Literature]Heat shock protein HSP 90-beta [gi:17865718]
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4
[SID103494091]
EC50 0.141Degradation of Her2 in SKBR3 cells [AID266550, Type: Literature]Heat shock protein HSP 90-beta [gi:17865718]
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5
[SID103494091]
GI50 0.724Inhibition of human SKBR3 cell growth [AID266548, Type: Literature]
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6
[SID103494091]
EC50 0.853Upregulation of Hsp70 in SKOV3 cells [AID266553, Type: Literature]Heat shock protein HSP 90-beta [gi:17865718]
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7
[SID103494091]
GI50 2.022Inhibition of human SKOV3 cell growth [AID266549, Type: Literature]
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8
[SID103494091]
EC50 4.585Degradation of Her2 in SKOV3 cells [AID266551, Type: Literature]Heat shock protein HSP 90-beta [gi:17865718]
View