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UNII-RDD1D7O9YX (CID 11786594) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(9)
 
 
Inactive(6)
 
 
Unspecified(7)
 
 
Top Targets:
CD36(9)
 
 
 
BioAssay Types:
Confirmatory(13)
 
 
 
Literature(9)
 
 
 
BioActivity Types:
AC50(11)
 
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 22    Data Row: 22   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID124360067]
AC50_uM 0.0114HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set9 [AID623880, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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2
[SID104236955]
IC50 0.038Inhibition of phospho-p38 alpha activity by ELISA [AID495022, Type: Literature]
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3
[SID104236955]
IC50 0.059Inhibition of p38 alpha activity by ELISA [AID495020, Type: Literature]
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4
[SID124360067]
AC50_uM 0.146HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set10 [AID624029, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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5
[SID124360067]
AbsAC40_uM 0.218HDL Orthogonal Assay: Alexa 488-HDL Measured in Cell-Based System Using Plate Reader - 2085-03_Inhibitor_Dose_DryPowder_Activity_Set3 [AID624024, Type: confirmatory]
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6
[SID124360067]
AbsAC40_uM 1.64HDL Orthogonal Assay: Alexa 488-HDL Measured in Cell-Based System Using Plate Reader - 2085-03_Inhibitor_Dose_DryPowder_Activity_Set2 [AID588810, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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7
[SID124360067]
AC50_uM 15.49HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-02_Inhibitor_Dose_DryPowder_Activity_Set4 [AID588842, Type: confirmatory]
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8
[SID124360067]
AC50_uM 17.84HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-02_Inhibitor_Dose_DryPowder_Activity_Set3 [AID588826, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
View
9
[SID124360067]
AC50_uM 34.35HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-02_Inhibitor_Dose_DryPowder_Activity_Set6 [AID623895, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
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10
[SID104236955]
Tmax in rat at 10 mg/kg, iv or 30 mg/kg, po [AID495024, Type: Literature]
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11
[SID104236955]
AUC in rat at 10 mg/kg, iv or 30 mg/kg, po [AID495025, Type: Literature]
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12
[SID104236955]
Cmax in rat at 10 mg/kg, iv or 30 mg/kg, po [AID495026, Type: Literature]
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13
[SID104236955]
Oral bioavailability in rat at 30 mg/kg, po [AID495027, Type: Literature]
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14
[SID104236955]
Half life in rat at 10 mg/kg, iv or 30 mg/kg, po [AID495028, Type: Literature]
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15
[SID104236955]
Clearance in rat at 10 mg/kg, iv or 30 mg/kg, po [AID495029, Type: Literature]
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16
[SID104236955]
Volume of distribution at steady state in rat at 10 mg/kg, iv or 30 mg/kg, po [AID495030, Type: Literature]
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17
[SID124360067]
AC50_uM HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set5 [AID588754, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
View
18
[SID124360067]
AC50_uM HDL Counter Assay: Tf Endo Assay Measured in Cell-Based System Using Plate Reader - 2085-04_Inhibitor_Dose_DryPowder_Activity [AID602134, Type: confirmatory]
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19
[SID124360067]
AC50_uM HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-02_Inhibitor_Dose_DryPowder_Activity_Set7 [AID624026, Type: confirmatory]
View
20
[SID124360067]
AC50_uM HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set6 [AID588828, Type: confirmatory]scavenger receptor class B member 1 isoform 1 [Mus musculus] [gi:14389423]
View