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GW682841X (CID 11717091) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(4)
 
 
Inconclusive(2)
 
 
Unspecified(456)
 
 
Top Targets:
PKc(43)
 
 
 
PKc like(42)
 
 
STKc AGC(16)
 
 
PTKc Abl(16)
 
 
PTKc Src like(11)
 
 
 
BioAssay Types:
Confirmatory(5)
 
 
 
Literature(4)
 
 
 
BioActivity Types:
Potency(7)
 
 
 
 
AC50(2)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 464    Data Row: 464   Total Pages: 24   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103483604]
IC50 0.032Displacement of rhodamine green fluorescently labeled ATP from recombinant GST-ALK5 by FP assay [AID262766, Type: Literature]TGF-beta receptor type-1 [gi:547777]
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2
[SID124349940]
Potency 23.1881qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen [AID686947, Type: Literature]tyrosine-protein kinase Yes [Homo sapiens] [gi:4885661]
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3
[SID103483604]
AC50 1.4566GSK_PKIS: Inhibition of Sea Pansy Luciferase (Data from PubChem: AID 652015) [NIH NCATS] [AID720834, Type: Literature]Renilla-luciferin 2-monooxygenase [gi:126502]
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4
[SID103483604]
GSK_PKIS: PDGFRB mean inhibition at 0.1 uM [Nanosyn] [AID651298, Type: other]Platelet-derived growth factor receptor beta [gi:129890]
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5
[SID103483604]
GSK_PKIS: PDGFRB mean inhibition at 1 uM [Nanosyn] [AID651299, Type: other]Platelet-derived growth factor receptor beta [gi:129890]
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6
[SID103483604]
GSK_PKIS: PDGFRA mean inhibition at 0.1 uM [Nanosyn] [AID651290, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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7
[SID103483604]
GSK_PKIS: PDGFRA mean inhibition at 1 uM [Nanosyn] [AID651291, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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8
[SID103483604]
GSK_PKIS: PDGFRA (D842V mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651292, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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9
[SID103483604]
GSK_PKIS: PDGFRA (D842V mutant) mean inhibition at 1 uM [Nanosyn] [AID651293, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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10
[SID103483604]
GSK_PKIS: PDGFRA (T674I mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651294, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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11
[SID103483604]
GSK_PKIS: PDGFRA (T674I mutant) mean inhibition at 1 uM [Nanosyn] [AID651295, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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12
[SID103483604]
GSK_PKIS: PDGFRA (V561D mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651296, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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13
[SID103483604]
GSK_PKIS: PDGFRA (V561D mutant) mean inhibition at 1 uM [Nanosyn] [AID651297, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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14
[SID103483604]
GSK_PKIS: CDK3/cyclinE mean inhibition at 0.1 uM [Nanosyn] [AID651168, Type: other]Cyclin-dependent kinase 3 [gi:231726]
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15
[SID103483604]
GSK_PKIS: CDK3/cyclinE mean inhibition at 1 uM [Nanosyn] [AID651169, Type: other]Cyclin-dependent kinase 3 [gi:231726]
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16
[SID103483604]
GSK_PKIS: MAPK3 mean inhibition at 0.1 uM [Nanosyn] [AID651198, Type: other]Mitogen-activated protein kinase 3 [gi:232066]
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17
[SID103483604]
GSK_PKIS: MAPK3 mean inhibition at 1 uM [Nanosyn] [AID651199, Type: other]Mitogen-activated protein kinase 3 [gi:232066]
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18
[SID103483604]
GSK_PKIS: CDK6/cyclinD3 mean inhibition at 0.1 uM [Nanosyn] [AID651174, Type: other]Cyclin-dependent kinase 6 [gi:266423]
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19
[SID103483604]
GSK_PKIS: CDK6/cyclinD3 mean inhibition at 1 uM [Nanosyn] [AID651175, Type: other]Cyclin-dependent kinase 6 [gi:266423]
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20
[SID103483604]
GSK_PKIS: MEK1 mean inhibition at 0.1 uM [Nanosyn] [AID651350, Type: other]Dual specificity mitogen-activated protein kinase kinase 1 [gi:400274]
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