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CHEMBL207247 (CID 11605761) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(8)
 
 
Inconclusive(4)
 
 
Unspecified(456)
 
 
Top Targets:
PKc like(42)
 
 
PKc(42)
 
 
STKc AGC(16)
 
 
PTKc Abl(16)
 
 
PTKc Src like(11)
 
 
 
BioAssay Types:
Literature(5)
 
 
 
 
Confirmatory(5)
 
 
 
BioActivity Types:
Potency(7)
 
 
 
AC50(2)
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 470    Data Row: 470   Total Pages: 24   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103486529]
IC50 0.052Inhibition of ErbB2 [AID263981, Type: Literature]Receptor tyrosine-protein kinase erbB-2 [gi:119533]
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2
[SID103486529]
IC50 0.06Inhibition of EGFR [AID263980, Type: Literature]Epidermal growth factor receptor [gi:2811086]
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3
[SID103486529]
GSK_PKIS: EGFR mean inhibition at 0.1 uM [Nanosyn] [AID651402, Type: other]Epidermal growth factor receptor [gi:2811086]
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4
[SID103486529]
GSK_PKIS: EGFR mean inhibition at 1 uM [Nanosyn] [AID651403, Type: other]Epidermal growth factor receptor [gi:2811086]
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5
[SID103486529]
GSK_PKIS: EGFR (L858R mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651404, Type: other]Epidermal growth factor receptor [gi:2811086]
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6
[SID103486529]
GSK_PKIS: EGFR (L858R mutant) mean inhibition at 1 uM [Nanosyn] [AID651405, Type: other]Epidermal growth factor receptor [gi:2811086]
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7
[SID103486529]
GSK_PKIS: EGFR (L861Q mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651406, Type: other]Epidermal growth factor receptor [gi:2811086]
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8
[SID103486529]
GSK_PKIS: EGFR (L861Q mutant) mean inhibition at 1 uM [Nanosyn] [AID651407, Type: other]Epidermal growth factor receptor [gi:2811086]
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9
[SID103486529]
GSK_PKIS: EGFR (T790M mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651408, Type: other]Epidermal growth factor receptor [gi:2811086]
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10
[SID103486529]
GSK_PKIS: EGFR (T790M mutant) mean inhibition at 1 uM [Nanosyn] [AID651409, Type: other]Epidermal growth factor receptor [gi:2811086]
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11
[SID103486529]
GSK_PKIS: EGFR (T790M-L858R mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651410, Type: other]Epidermal growth factor receptor [gi:2811086]
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12
[SID103486529]
GSK_PKIS: EGFR (T790M-L858R mutant) mean inhibition at 1 uM [Nanosyn] [AID651411, Type: other]Epidermal growth factor receptor [gi:2811086]
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13
[SID103486529]
GSK_PKIS: PHKG1 mean inhibition at 0.1 uM [Nanosyn] [AID651132, Type: other]Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform [gi:2833281]
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14
[SID103486529]
GSK_PKIS: PHKG1 mean inhibition at 1 uM [Nanosyn] [AID651133, Type: other]Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform [gi:2833281]
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15
[SID103486529]
GSK_PKIS: P38gamma mean inhibition at 0.1 uM [Nanosyn] [AID651208, Type: other]Mitogen-activated protein kinase 12 [gi:2851522]
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16
[SID103486529]
GSK_PKIS: P38gamma mean inhibition at 1 uM [Nanosyn] [AID651209, Type: other]Mitogen-activated protein kinase 12 [gi:2851522]
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17
[SID103486529]
GSK_PKIS: CK1-g2 mean inhibition at 0.1 uM [Nanosyn] [AID651158, Type: other]Casein kinase I isoform gamma-2 [gi:3024060]
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18
[SID103486529]
GSK_PKIS: CK1-g2 mean inhibition at 1 uM [Nanosyn] [AID651159, Type: other]Casein kinase I isoform gamma-2 [gi:3024060]
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19
[SID103486529]
GSK_PKIS: PYK2 mean inhibition at 0.1 uM [Nanosyn] [AID651302, Type: other]Protein-tyrosine kinase 2-beta [gi:3183003]
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20
[SID103486529]
GSK_PKIS: PYK2 mean inhibition at 1 uM [Nanosyn] [AID651303, Type: other]Protein-tyrosine kinase 2-beta [gi:3183003]
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