CHEMBL204091 (CID 11499925) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(1)
 
 
Unspecified(7)
 
 
Top Targets:
Neur chan LBD(1)
 
 
BioAssay Types:
Literature(8)
 
 
 
BioActivity Types:
Ki(1)
 
 
SAR
Target summary
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 8   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103481443]
Ki 4.29Binding affinity to Wistar rat benzodiazepine receptor [AID261133, Type: Literature]Gamma-aminobutyric acid receptor subunit pi [gi:3023821]
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2
[SID103481443]
 Neurotoxicological activity in NMRI BR mice after ip administration by rotarod test [AID261136, Type: Literature]
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3
[SID103481443]
 Anxiolytic activity in rat after oral administration by PTZ test [AID261137, Type: Literature]
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4
[SID103481443]
 Anxiolytic activity in rat after oral administration by vogel conflict test [AID261138, Type: Literature]
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5
[SID103481443]
 Neurotoxicological activity in rat after oral administration by rotarod test [AID261139, Type: Literature]
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6
[SID103481443]
 Protective index (PI=TD50/ED50) in rat after oral administration [AID261140, Type: Literature]
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7
[SID103481443]
 Anxiolytic activity in NMRI BR mice after ip administration by PTZ test [AID261135, Type: Literature]
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8
[SID103481443]
 Partition coefficient of the compound, log P [AID261132, Type: Literature]
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