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1-(carboxymethylthio)tetradecane (CID 114924) - Compound BioActivity Data
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BioActivity Outcomes:
Active(13)
 
 
Inactive(258)
 
 
Inconclusive(41)
 
 
Unspecified(37)
 
 
Top Targets:
p450(9)
 
 
 
NR LBD TR(8)
 
 
 
7TM GPCR Srx(7)
 
 
 
ANK(6)
 
 
 
PLN02808(6)
 
 
BioAssay Types:
Confirmatory(267)
 
 
 
 
 
Literature(44)
 
 
 
 
Screening(13)
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(242)
 
 
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 289    Data Row: 349   Total Pages: 18   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26753658]
Potency 10qHTS assay for small molecule agonists of the peroxisome proliferator-activated receptor alpha (PPARalpha) signaling pathway [AID651778, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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2
[SID90340854]
Potency 10qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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3
[SID90340854]
Potency 23.9341qHTS Validation Assay to Find Inhibitors of Pin1 [AID504536, Type: confirmatory]peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [Homo sapiens] [gi:5453898]
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4
[SID90340854]
Potency 25.1189Inhibitors of USP1/UAF1: Pilot qHTS [AID504865, Type: confirmatory]USP1 protein [Homo sapiens] [gi:118600387]
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5
[SID26753658]
Potency 28.1838qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling [AID588536, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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6
[SID85231250]
Potency 31.6228qHTS Validation Assay for Inhibitors for MPP8 Chromodomain Interactions with Methylated Histone Tails [AID488949, Type: confirmatory]M-phase phosphoprotein 8 [Homo sapiens] [gi:41055989]
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7
[SID103456707]
IC50 43Concentration required for inhibition of lipid synthesis in primary cultures of rat hepatocytes [AID248137, Type: Literature]
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8
[SID90340854]
Potency 50.1187qHTS Validation Assay for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID488953, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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9
[SID17405711]
HTS of LOPAC library for Estrogen Receptor-alpha Coactivator Binding inhibitors [AID694, Type: confirmatory]Estrogen receptor 1 [Homo sapiens] [gi:118764400]
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10
[SID17405711]
HTS for BAP1 Enzyme inhibitors [AID436, Type: screening]Ubiquitin carboxyl-terminal hydrolase BAP1 [gi:68565074]
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11
[SID103456707]
Activation of PPARalpha expressed in human MCF7 cells at 30 uM by luciferase reporter gene assay [AID476931, Type: Literature]
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12
[SID103456707]
Activation of PPARdelta expressed in human MCF7 cells at 30 uM by luciferase reporter gene assay [AID476933, Type: Literature]
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13
[SID103456707]
Activation of PPARgamma expressed in human MCF7 cells at 30 uM by luciferase reporter gene assay [AID476935, Type: Literature]
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14
[SID26753658]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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15
[SID103456707]
Decrease in plasma cholesterol level in po dosed Wistar rat after 6 days [AID346092, Type: Literature]
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16
[SID103456707]
Decrease in plasma triacylglycerol level in po dosed Wistar rat after 6 days [AID346093, Type: Literature]
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17
[SID103456707]
Induction of PPAR-alpha-regulated HMG-CoA synthase activity in po dosed Wistar rat after 6 days [AID346098, Type: Literature]
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18
[SID103456707]
Induction of PPAR-alpha-regulated fatty acyl-CoA oxidase activity in po dosed Wistar rat after 6 days [AID346099, Type: Literature]
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19
[SID103456707]
Induction of PPAR-alpha-regulated CPT2 activity in po dosed Wistar rat after 6 days [AID346102, Type: Literature]
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20
[SID103456707]
Increase in [1-14C]palmitoyl-CoA oxidation in po dosed Wistar rat liver homogenate after 6 days [AID346104, Type: Literature]
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