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Allethrin (CID 11442) - Compound BioActivity Data
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BioActivity Outcomes:
Active(38)
 
 
Inactive(85)
 
 
Inconclusive(53)
 
 
Unspecified(7)
 
 
Top Targets:
NR LBD PPAR(18)
 
 
 
NR LBD AR(11)
 
 
 
 
NR LBD TR(11)
 
 
 
 
NR LBD ER(11)
 
 
 
 
NR LBD Fxr(8)
 
 
 
BioAssay Types:
Confirmatory(134)
 
 
 
 
Summary(24)
 
 
 
 
Screening(2)
 
 
Literature(1)
 
 
BioActivity Types:
Potency(152)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 135    Data Row: 183   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144214035]
Potency-Replicate_1 5.7768qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID144214035]
Potency-Replicate_1 5.7768qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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3
[SID144214035]
Potency-Replicate_1 5.7768qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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4
[SID144214035]
Potency-Replicate_1 10.2727qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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5
[SID144214035]
Potency-Replicate_1 11.5262qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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6
[SID26757370]
Potency 12.5893qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway [AID651751, Type: confirmatory]pregnane X receptor [Rattus norvegicus] [gi:5702233]
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7
[SID26757890]
Potency-Replicate_1 12.5893qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
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8
[SID144214035]
Potency-Replicate_1 18.2678qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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9
[SID144214035]
Potency-Replicate_1 18.2678qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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10
[SID144214035]
Potency-Replicate_1 18.4249qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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11
[SID144214035]
Potency-Replicate_1 23.1955qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
View
12
[SID144214035]
Potency-Replicate_1 23.1955qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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13
[SID144214035]
Potency 24.3365qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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14
[SID144214035]
Potency-Replicate_1 25.8039qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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15
[SID144214035]
Potency-Replicate_1 25.8039qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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16
[SID144214035]
Potency 28.1838qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
View
17
[SID144214035]
Potency-Replicate_1 28.9525qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
View
18
[SID144214035]
Potency-Replicate_1 32.7646qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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19
[SID144214035]
Potency-Replicate_1 36.449qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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20
[SID26757370]
Potency-Replicate_1 39.8107qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
View