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KW 2449 (CID 11427553) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(318)
 
 
Unspecified(124)
 
 
Top Targets:
PKc(48)
 
 
 
PKc like(40)
 
 
 
STKc AGC(17)
 
 
 
PTKc Abl(16)
 
 
PTKc EGFR(12)
 
 
 
BioAssay Types:
Literature(442)
 
 
 
BioActivity Types:
Kd(442)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 442    Data Row: 442   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136944791]
Kd 0.0029Binding constant for DRAK1 kinase domain [AID624968, Type: Literature]Serine/threonine-protein kinase 17A [gi:317373279]
View
2
[SID136944791]
Kd 0.0043Binding constant for MLCK kinase domain [AID624738, Type: Literature]Myosin light chain kinase 3 [gi:254763411]
View
3
[SID136944791]
Kd 0.0048Binding constant for DRAK2 kinase domain [AID624942, Type: Literature]Serine/threonine-protein kinase 17B [gi:14423909]
View
4
[SID136944791]
Kd 0.0052Binding constant for YSK4 kinase domain [AID625136, Type: Literature]Mitogen-activated protein kinase kinase kinase 19 [gi:74755104]
View
5
[SID136944791]
Kd 0.0059Binding constant for ABL1(T315I)-phosphorylated kinase domain [AID624989, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
6
[SID136944791]
Kd 0.0066Binding constant for FLT3(K663Q) kinase domain [AID624938, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
7
[SID136944791]
Kd 0.0096Binding constant for BIKE kinase domain [AID625109, Type: Literature]BMP-2-inducible protein kinase [gi:34222653]
View
8
[SID136944791]
Kd 0.011Binding constant for MAP4K2 kinase domain [AID624959, Type: Literature]Mitogen-activated protein kinase kinase kinase kinase 2 [gi:215274019]
View
9
[SID136944791]
Kd 0.012Binding constant for ABL1(T315I)-nonphosphorylated kinase domain [AID624988, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
10
[SID136944791]
Kd 0.012Binding constant for KIT(V559D,T670I) kinase domain [AID624792, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
11
[SID136944791]
Kd 0.013Binding constant for LOK kinase domain [AID625030, Type: Literature]Serine/threonine-protein kinase 10 [gi:12643358]
View
12
[SID136944791]
Kd 0.013Binding constant for SLK kinase domain [AID625086, Type: Literature]STE20-like serine/threonine-protein kinase [gi:74762732]
View
13
[SID136944791]
Kd 0.013Binding constant for FLT3(N841I) kinase domain [AID624939, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
14
[SID136944791]
Kd 0.013Binding constant for FLT3(D835H) kinase domain [AID624935, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
15
[SID136944791]
Kd 0.013Binding constant for FLT3(D835Y) kinase domain [AID624936, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
16
[SID136944791]
Kd 0.015Binding constant for FLT3 kinase domain [AID624934, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
17
[SID136944791]
Kd 0.015Binding constant for SRPK2 kinase domain [AID624768, Type: Literature]SRSF protein kinase 2 [gi:300669676]
View
18
[SID136944791]
Kd 0.017Binding constant for ABL1(H396P)-nonphosphorylated kinase domain [AID624983, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
19
[SID136944791]
Kd 0.018Binding constant for YES kinase domain [AID625018, Type: Literature]Tyrosine-protein kinase Yes [gi:125870]
View
20
[SID136944791]
Kd 0.019Binding constant for ABL1(M351T)-phosphorylated kinase domain [AID624985, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
21
[SID136944791]
Kd 0.02Binding constant for FLT3(ITD) kinase domain [AID624937, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
22
[SID136944791]
Kd 0.021Binding constant for PLK4 kinase domain [AID625076, Type: Literature]Serine/threonine-protein kinase PLK4 [gi:160113150]
View
23
[SID136944791]
Kd 0.021Binding constant for KIT(L576P) kinase domain [AID624790, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
24
[SID136944791]
Kd 0.022Binding constant for ABL1(Q252H)-phosphorylated kinase domain [AID624987, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
25
[SID136944791]
Kd 0.023Binding constant for KIT(V559D) kinase domain [AID624791, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
26
[SID136944791]
Kd 0.024Binding constant for ABL1(H396P)-phosphorylated kinase domain [AID624984, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
27
[SID136944791]
Kd 0.025Binding constant for MINK kinase domain [AID624813, Type: Literature]Misshapen-like kinase 1 [gi:296437370]
View
28
[SID136944791]
Kd 0.028Binding constant for TNIK kinase domain [AID625093, Type: Literature]TRAF2 and NCK-interacting protein kinase [gi:29840818]
View
29
[SID136944791]
Kd 0.029Binding constant for STK16 kinase domain [AID624775, Type: Literature]Serine/threonine-protein kinase 16 [gi:46577677]
View
30
[SID136944791]
Kd 0.03Binding constant for PDGFRB kinase domain [AID624875, Type: Literature]Platelet-derived growth factor receptor beta [gi:129890]
View
31
[SID136944791]
Kd 0.033Binding constant for MAP4K4 kinase domain [AID624756, Type: Literature]Mitogen-activated protein kinase kinase kinase kinase 4 [gi:29427585]
View
32
[SID136944791]
Kd 0.035Binding constant for RET(V804L) kinase domain [AID625123, Type: Literature]Proto-oncogene tyrosine-protein kinase receptor Ret [gi:547807]
View
33
[SID136944791]
Kd 0.035Binding constant for RET(V804M) kinase domain [AID625124, Type: Literature]Proto-oncogene tyrosine-protein kinase receptor Ret [gi:547807]
View
34
[SID136944791]
Kd 0.036Binding constant for TAK1 kinase domain [AID624724, Type: Literature]Mitogen-activated protein kinase kinase kinase 7 [gi:12643557]
View
35
[SID136944791]
Kd 0.036Binding constant for ABL1(E255K)-phosphorylated kinase domain [AID624978, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
36
[SID136944791]
Kd 0.036Binding constant for ABL1(Y253F)-phosphorylated kinase domain [AID624990, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
37
[SID136944791]
Kd 0.039Binding constant for JAK3(JH1domain-catalytic) kinase domain [AID624785, Type: Literature]Tyrosine-protein kinase JAK3 [gi:50403745]
View
38
[SID136944791]
Kd 0.045Binding constant for LRRK2(G2019S) kinase domain [AID624741, Type: Literature]Leucine-rich repeat serine/threonine-protein kinase 2 [gi:294862450]
View
39
[SID136944791]
Kd 0.047Binding constant for RIOK1 kinase domain [AID625141, Type: Literature]Serine/threonine-protein kinase RIO1 [gi:56404949]
View
40
[SID136944791]
Kd 0.047Binding constant for ABL1(Q252H)-nonphosphorylated kinase domain [AID624986, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
41
[SID136944791]
Kd 0.047Binding constant for RET(M918T) kinase domain [AID625122, Type: Literature]Proto-oncogene tyrosine-protein kinase receptor Ret [gi:547807]
View
42
[SID136944791]
Kd 0.048Binding constant for IRAK1 kinase domain [AID624837, Type: Literature]Interleukin-1 receptor-associated kinase 1 [gi:8928535]
View
43
[SID136944791]
Kd 0.048Binding constant for AAK1 kinase domain [AID625089, Type: Literature]AP2-associated protein kinase 1 [gi:300669613]
View
44
[SID136944791]
Kd 0.049Binding constant for CLK4 kinase domain [AID625125, Type: Literature]Dual specificity protein kinase CLK4 [gi:34922132]
View
45
[SID136944791]
Kd 0.051Binding constant for PIP5K1A kinase domain [AID624824, Type: Literature]Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha [gi:74752158]
View
46
[SID136944791]
Kd 0.051Binding constant for JNK3 kinase domain [AID624891, Type: Literature]Mitogen-activated protein kinase 10 [gi:2507196]
View
47
[SID136944791]
Kd 0.052Binding constant for MYLK2 kinase domain [AID624705, Type: Literature]Myosin light chain kinase 2, skeletal/cardiac muscle [gi:24211884]
View
48
[SID136944791]
Kd 0.053Binding constant for KIT kinase domain [AID624786, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
49
[SID136944791]
Kd 0.053Binding constant for ULK1 kinase domain [AID624916, Type: Literature]Serine/threonine-protein kinase ULK1 [gi:317373288]
View
50
[SID136944791]
Kd 0.054Binding constant for SNARK kinase domain [AID625139, Type: Literature]NUAK family SNF1-like kinase 2 [gi:74761376]
View