KW 2449 (CID 11427553) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(318)
 
 
Unspecified(124)
 
 
Top Targets:
PKc(55)
 
 
 
PKc like(34)
 
 
 
STKc AGC(24)
 
 
 
PTKc Abl(16)
 
 
PTKc EGFR(12)
 
 
 
BioAssay Types:
Literature(442)
 
 
 
BioActivity Types:
Kd(442)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 442    Data Row: 442   Total Pages: 9   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136944791]
Kd 0.0029Binding constant for DRAK1 kinase domain [AID624968, Type: Literature]Serine/threonine-protein kinase 17A [gi:317373279]
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2
[SID136944791]
Kd 0.0029Binding constant for DRAK1 kinase domain [AID624968, Type: Literature]Serine/threonine-protein kinase 17A [gi:317373279]
View
3
[SID136944791]
Kd 0.0043Binding constant for MLCK kinase domain [AID624738, Type: Literature]Myosin light chain kinase 3 [gi:254763411]
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4
[SID136944791]
Kd 0.0043Binding constant for MLCK kinase domain [AID624738, Type: Literature]Myosin light chain kinase 3 [gi:254763411]
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5
[SID136944791]
Kd 0.0048Binding constant for DRAK2 kinase domain [AID624942, Type: Literature]Serine/threonine-protein kinase 17B [gi:14423909]
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6
[SID136944791]
Kd 0.0048Binding constant for DRAK2 kinase domain [AID624942, Type: Literature]Serine/threonine-protein kinase 17B [gi:14423909]
View
7
[SID136944791]
Kd 0.0052Binding constant for YSK4 kinase domain [AID625136, Type: Literature]Mitogen-activated protein kinase kinase kinase 19 [gi:74755104]
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8
[SID136944791]
Kd 0.0059Binding constant for ABL1(T315I)-phosphorylated kinase domain [AID624989, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
9
[SID136944791]
Kd 0.0059Binding constant for ABL1(T315I)-phosphorylated kinase domain [AID624989, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
10
[SID136944791]
Kd 0.0066Binding constant for FLT3(K663Q) kinase domain [AID624938, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
11
[SID136944791]
Kd 0.0066Binding constant for FLT3(K663Q) kinase domain [AID624938, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
12
[SID136944791]
Kd 0.0066Binding constant for FLT3(K663Q) kinase domain [AID624938, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
13
[SID136944791]
Kd 0.0096Binding constant for BIKE kinase domain [AID625109, Type: Literature]BMP-2-inducible protein kinase [gi:34222653]
View
14
[SID136944791]
Kd 0.0096Binding constant for BIKE kinase domain [AID625109, Type: Literature]BMP-2-inducible protein kinase [gi:34222653]
View
15
[SID136944791]
Kd 0.011Binding constant for MAP4K2 kinase domain [AID624959, Type: Literature]Mitogen-activated protein kinase kinase kinase kinase 2 [gi:215274019]
View
16
[SID136944791]
Kd 0.011Binding constant for MAP4K2 kinase domain [AID624959, Type: Literature]Mitogen-activated protein kinase kinase kinase kinase 2 [gi:215274019]
View
17
[SID136944791]
Kd 0.012Binding constant for KIT(V559D,T670I) kinase domain [AID624792, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
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18
[SID136944791]
Kd 0.012Binding constant for KIT(V559D,T670I) kinase domain [AID624792, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
19
[SID136944791]
Kd 0.012Binding constant for ABL1(T315I)-nonphosphorylated kinase domain [AID624988, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
20
[SID136944791]
Kd 0.012Binding constant for ABL1(T315I)-nonphosphorylated kinase domain [AID624988, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
21
[SID136944791]
Kd 0.013Binding constant for FLT3(N841I) kinase domain [AID624939, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
22
[SID136944791]
Kd 0.013Binding constant for FLT3(N841I) kinase domain [AID624939, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
23
[SID136944791]
Kd 0.013Binding constant for FLT3(N841I) kinase domain [AID624939, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
24
[SID136944791]
Kd 0.013Binding constant for FLT3(D835H) kinase domain [AID624935, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
25
[SID136944791]
Kd 0.013Binding constant for FLT3(D835H) kinase domain [AID624935, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
26
[SID136944791]
Kd 0.013Binding constant for FLT3(D835H) kinase domain [AID624935, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
27
[SID136944791]
Kd 0.013Binding constant for FLT3(D835Y) kinase domain [AID624936, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
28
[SID136944791]
Kd 0.013Binding constant for FLT3(D835Y) kinase domain [AID624936, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
29
[SID136944791]
Kd 0.013Binding constant for FLT3(D835Y) kinase domain [AID624936, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
30
[SID136944791]
Kd 0.013Binding constant for LOK kinase domain [AID625030, Type: Literature]Serine/threonine-protein kinase 10 [gi:12643358]
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31
[SID136944791]
Kd 0.013Binding constant for LOK kinase domain [AID625030, Type: Literature]Serine/threonine-protein kinase 10 [gi:12643358]
View
32
[SID136944791]
Kd 0.013Binding constant for SLK kinase domain [AID625086, Type: Literature]STE20-like serine/threonine-protein kinase [gi:74762732]
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33
[SID136944791]
Kd 0.013Binding constant for SLK kinase domain [AID625086, Type: Literature]STE20-like serine/threonine-protein kinase [gi:74762732]
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34
[SID136944791]
Kd 0.015Binding constant for SRPK2 kinase domain [AID624768, Type: Literature]SRSF protein kinase 2 [gi:300669676]
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35
[SID136944791]
Kd 0.015Binding constant for SRPK2 kinase domain [AID624768, Type: Literature]SRSF protein kinase 2 [gi:300669676]
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36
[SID136944791]
Kd 0.015Binding constant for FLT3 kinase domain [AID624934, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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37
[SID136944791]
Kd 0.015Binding constant for FLT3 kinase domain [AID624934, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
38
[SID136944791]
Kd 0.015Binding constant for FLT3 kinase domain [AID624934, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
39
[SID136944791]
Kd 0.017Binding constant for ABL1(H396P)-nonphosphorylated kinase domain [AID624983, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
40
[SID136944791]
Kd 0.017Binding constant for ABL1(H396P)-nonphosphorylated kinase domain [AID624983, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
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41
[SID136944791]
Kd 0.018Binding constant for YES kinase domain [AID625018, Type: Literature]Tyrosine-protein kinase Yes [gi:125870]
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42
[SID136944791]
Kd 0.018Binding constant for YES kinase domain [AID625018, Type: Literature]Tyrosine-protein kinase Yes [gi:125870]
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43
[SID136944791]
Kd 0.019Binding constant for ABL1(M351T)-phosphorylated kinase domain [AID624985, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
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44
[SID136944791]
Kd 0.019Binding constant for ABL1(M351T)-phosphorylated kinase domain [AID624985, Type: Literature]Tyrosine-protein kinase ABL1 [gi:85681908]
View
45
[SID136944791]
Kd 0.02Binding constant for FLT3(ITD) kinase domain [AID624937, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
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46
[SID136944791]
Kd 0.02Binding constant for FLT3(ITD) kinase domain [AID624937, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
47
[SID136944791]
Kd 0.02Binding constant for FLT3(ITD) kinase domain [AID624937, Type: Literature]Receptor-type tyrosine-protein kinase FLT3 [gi:156630887]
View
48
[SID136944791]
Kd 0.021Binding constant for KIT(L576P) kinase domain [AID624790, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
49
[SID136944791]
Kd 0.021Binding constant for KIT(L576P) kinase domain [AID624790, Type: Literature]Mast/stem cell growth factor receptor Kit [gi:125472]
View
50
[SID136944791]
Kd 0.021Binding constant for PLK4 kinase domain [AID625076, Type: Literature]Serine/threonine-protein kinase PLK4 [gi:160113150]
View