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BioActivity Data for Compound Thymine (CID 1135)

BioActivity Outcomes:
Active(1)
 
 
Inactive(17)
 
 
Inconclusive(4)
 
 
Unspecified(7)
 
 
BioAssay Types:
Literature(13)
 
 
 
 
BioAssay Categories:
In vivo(10)
 
 
 
 
Biochemical(1)
 
 
Toxicity(5)
 
 
 
ADME(1)
 
 
Cell-based(10)
 
 
 
BioActivity Types:
IC50(3)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 29    Data Row: 29   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID78806]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Mammary Adenocarcinoma CD8F1 (subcutaneous) in CD8F1 [AID220, Type: other]
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2
[SID103263715]
IC50 100Cytotoxicity was determined in CEM cells, relative to RVT [AID47311, Type: Literature]
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3
[SID103263715]
IC50 100Cytotoxicity was determined in Vero cells, relative to RVT [AID217732, Type: Literature]
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4
[SID103263715]
IC50 100Cytotoxicity was determined in PBM cells, relative to RVT [AID155299, Type: Literature]
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5
[SID103263715]
Ki 347000Inhibitory activity against mouse liver thymidine phosphorylase at 0.15 mM thymidine substrate [AID211081, Type: Literature]
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6
[SID103263715]
Cytotoxicity against MDCK cells [AID501988, Type: Literature]
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7
[SID103263715]
Antiviral activity against Influenza B virus Florida/4/2006 infected in MDCK cells [AID501987, Type: Literature]
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8
[SID103263715]
Antiviral activity against Influenza A virus H5N1 Vietnam/1203/2004H infected in MDCK cells [AID501986, Type: Literature]
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9
[SID103263715]
Cytotoxicity against human KB cells at 30 uM [AID477229, Type: Literature]
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10
[SID103263715]
Antitumor activity against mouse B16 cells allografted in C57Bl/6 mouse at 25 mg/kg/day, ip administered for 2 weeks relative to control [AID1149715, Type: Literature]
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11
[SID103263715]
Antitumor activity against mouse P388 cells allografted in DBA/2 mouse at 25 mg/kg/day, ip administered for 2 weeks relative to control [AID1149714, Type: Literature]
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12
[SID103263715]
Antitumor activity against rat Walker 256 cells allografted in Sprague-Dawley rat at 2.5 mg/kg/day, ip relative to control [AID1149713, Type: Literature]
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13
[SID78806]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Madison 109 Lung Carcinoma (intramuscular) in BALB/CM mice [AID302, Type: other]
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14
[SID78806]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Lewis Lung Carcinoma (intravenous) in B6D2F1 (BDF1) mice [AID274, Type: other]
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15
[SID78806]
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID248, Type: other]
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16
[SID78806]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Ependymoblastoma (intracerebral) in B6C3F1 mice [AID226, Type: other]
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17
[SID78806]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Ependymoblastoma (intracerebral) in C57BL/6 mice [AID222, Type: other]
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18
[SID78806]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID330, Type: other]
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19
[SID78806]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Colon 26 Adenocarcinoma (intraperitoneal) in CD2F1 (CDF1) mice [AID210, Type: other]
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20
[SID78806]
NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
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