2-mercaptoacetate (CID 1133) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(1)
 
 
Inactive(55)
 
 
Unspecified(4)
 
 
BioAssay Types:
Confirmatory(53)
 
 
Literature(5)
 
 
 
BioActivity Types:
IC50(3)
 
 
Ki(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 60    Data Row: 60   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103341946]
Ki 0.18Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysis [AID575011, Type: Literature]Metallo-beta-lactamase IMP-1 (Beta-lactamase IMP-1) (Metallo-beta-lactamase) (IMP-1 metallo-beta-lac [gi:75521105]
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2
[SID103341946]
IC50 200Inhibitory concentration inducing 50% decrease in HeLa cell survival [AID247922, Type: Literature]
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3
[SID103341946]
IC50 200Inhibitory concentration that required to induce 50% decrease in PBMC (healthy human?s peripheral blood cells) cells survival [AID248860, Type: Literature]
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4
[SID103341946]
IC50 200Inhibitory concentration that required to induce 50% decrease in PBMC+PHA (healthy human?s peripheral blood cells) cells survival [AID248907, Type: Literature]
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5
[SID103341946]
 Partition coefficient (logP) [AID23443, Type: Literature]
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6
[SID68624]
 NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID248, Type: other]
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7
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line [AID145, Type: confirmatory]
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8
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line [AID143, Type: confirmatory]
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9
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the NCI-H460 Non-Small Cell Lung cell line [AID7, Type: confirmatory]
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10
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line [AID13, Type: confirmatory]
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11
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the NCI-H522 Non-Small Cell Lung cell line [AID15, Type: confirmatory]
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12
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the LXFL 529 Non-Small Cell Lung cell line [AID17, Type: confirmatory]
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13
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the A549/ATCC Non-Small Cell Lung cell line [AID19, Type: confirmatory]
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14
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the EKVX Non-Small Cell Lung cell line [AID21, Type: confirmatory]
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15
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the LOX IMVI Melanoma cell line [AID23, Type: confirmatory]
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16
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the M19-MEL Melanoma cell line [AID27, Type: confirmatory]
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17
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line [AID29, Type: confirmatory]
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18
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the UACC-62 Melanoma cell line [AID31, Type: confirmatory]
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19
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the UACC-257 Melanoma cell line [AID33, Type: confirmatory]
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20
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-2 Melanoma cell line [AID35, Type: confirmatory]
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21
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line [AID37, Type: confirmatory]
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22
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-28 Melanoma cell line [AID39, Type: confirmatory]
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23
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the SF-268 Central Nervous System cell line [AID45, Type: confirmatory]
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24
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the SF-295 Central Nervous System cell line [AID47, Type: confirmatory]
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25
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line [AID49, Type: confirmatory]
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26
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the XF 498 Central Nervous System cell line [AID51, Type: confirmatory]
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27
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the SNB-19 Central Nervous System cell line [AID53, Type: confirmatory]
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28
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the SNB-75 Central Nervous System cell line [AID55, Type: confirmatory]
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29
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the SNB-78 Central Nervous System cell line [AID57, Type: confirmatory]
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30
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the U251 Central Nervous System cell line [AID59, Type: confirmatory]
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31
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the DMS 273 Small Cell Lung cell line [AID61, Type: confirmatory]
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32
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the DMS 114 Small Cell Lung cell line [AID63, Type: confirmatory]
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33
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the HT29 Colon cell line [AID65, Type: confirmatory]
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34
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the COLO 205 Colon cell line [AID67, Type: confirmatory]
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35
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the DLD-1 Colon cell line [AID69, Type: confirmatory]
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36
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the HCT-15 Colon cell line [AID71, Type: confirmatory]
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37
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the KM12 Colon cell line [AID73, Type: confirmatory]
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38
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the KM20L2 Colon cell line [AID75, Type: confirmatory]
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39
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the HCC-2998 Colon cell line [AID77, Type: confirmatory]
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40
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the HCT-116 Colon cell line [AID79, Type: confirmatory]
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41
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the SW-620 Colon cell line [AID81, Type: confirmatory]
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42
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the NCI-H322M Non-Small Cell Lung cell line [AID5, Type: confirmatory]
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43
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the NCI-H226 Non-Small Cell Lung cell line [AID3, Type: confirmatory]
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44
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line [AID1, Type: confirmatory]
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45
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Ovarian cell line [AID101, Type: confirmatory]
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46
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the SK-OV-3 Ovarian cell line [AID103, Type: confirmatory]
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47
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the OVCAR-4 Ovarian cell line [AID105, Type: confirmatory]
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48
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the OVCAR-5 Ovarian cell line [AID107, Type: confirmatory]
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49
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the RPMI-8226 Leukemia cell line [AID113, Type: confirmatory]
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50
[SID68624]
 NCI human tumor cell line growth inhibition assay. Data for the SR Leukemia cell line [AID115, Type: confirmatory]
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