Bookmark and Share
CHEMBL584478 (CID 11325594) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(2)
 
 
Unspecified(4)
 
 
Top Targets:
PBP1 mGluR gr..(2)
 
 
BioAssay Types:
Literature(6)
 
 
 
BioActivity Types:
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 6   Total Pages: 1   
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103702515]
IC50 0.0055Antagonist activity at human mGluR1 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FLIPR [AID446923, Type: Literature]Metabotropic glutamate receptor 1 [gi:311033443]
View
2
[SID103702515]
IC50 2.3Antagonist activity at human mGluR5 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FLIPR [AID446924, Type: Literature]Metabotropic glutamate receptor 5 [gi:1709020]
View
3
[SID103702515]
Octanol to water distribution coefficient, log D at pH 7.4 [AID446925, Type: Literature]
View
4
[SID103702515]
Oral bioavailability in rat at 3 mg/kg [AID446926, Type: Literature]
View
5
[SID103702515]
Half life in rat at 3 mg/kg, po and 1 mg/kg, iv [AID446927, Type: Literature]
View
6
[SID103702515]
Plasma clearance in rat at 3 mg/kg, po and 1 mg/kg, iv [AID446928, Type: Literature]
View