Thiamine Pyrophosphate (CID 1132) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(6)
 
 
Inactive(115)
 
 
Inconclusive(2)
 
 
Unspecified(1)
 
 
Top Targets:
TPP E1 PDC AD..(5)
 
 
NR LBD TR(4)
 
 
NR LBD ROR li..(4)
 
 
Menin(4)
 
 
HELICc(3)
 
 
BioAssay Types:
Literature(68)
 
 
 
 
Confirmatory(53)
 
 
 
Screening(3)
 
 
BioActivity Types:
Potency(51)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 45    Data Row: 124   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46392800]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Roles Of His291-Alpha And His146-Beta' In The Reductive Acylation Reaction Catalyzed By Hum [gi:34810147]
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2
[SID46392801]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Roles Of His291-Alpha And His146-Beta' In The Reductive Acylation Reaction Catalyzed By Hum [gi:34810149]
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3
[SID46392802]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Roles Of His291-alpha And His146-beta' In The Reductive Acylation Reaction Catalyzed By Hum [gi:34810151]
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4
[SID46393382]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Crosstalk Between Cofactor Binding And The Phosphorylation Loop Conformation In The Bckd Ma [gi:49259445]
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5
[SID46393383]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Crosstalk Between Cofactor Binding And The Phosphorylation Loop Conformation In The Bckd Ma [gi:49259447]
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6
[SID46393386]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature] [gi:49259450]
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7
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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8
[SID29216306]
Potency 28.6954Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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9
[SID29216307]
Potency qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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10
[SID29216306]
Potency qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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11
[SID29216307]
Potency qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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12
[SID29216306]
Potency qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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13
[SID29216307]
Potency qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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14
[SID29216307]
 Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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15
[SID29216307]
 A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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16
[SID29216307]
Potency qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia [AID1477, Type: confirmatory]
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17
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_1, Type: Literature]
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18
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_2, Type: Literature]
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19
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_3, Type: Literature]
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20
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_4, Type: Literature]
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21
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_5, Type: Literature]
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22
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_6, Type: Literature]
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23
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_7, Type: Literature]
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24
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_8, Type: Literature]
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25
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_9, Type: Literature]
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26
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_10, Type: Literature]
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27
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_11, Type: Literature]
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28
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_12, Type: Literature]
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29
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_13, Type: Literature]
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30
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_14, Type: Literature]
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31
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_15, Type: Literature]
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32
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_16, Type: Literature]
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33
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_17, Type: Literature]
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34
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_18, Type: Literature]
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35
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_19, Type: Literature]
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36
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_20, Type: Literature]
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37
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_21, Type: Literature]
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38
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_22, Type: Literature]
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39
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_23, Type: Literature]
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40
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_24, Type: Literature]
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41
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_25, Type: Literature]
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42
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_26, Type: Literature]
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43
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_27, Type: Literature]
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44
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_28, Type: Literature]
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45
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_29, Type: Literature]
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46
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_30, Type: Literature]
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47
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_31, Type: Literature]
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48
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_32, Type: Literature]
View
49
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_33, Type: Literature]
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50
[SID29216306]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_34, Type: Literature]
View