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Thiamine Pyrophosphate (CID 1132) - Compound BioActivity Data
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BioActivity Outcomes:
Active(15)
 
 
Inactive(124)
 
 
Inconclusive(2)
 
 
Unspecified(1)
 
 
Top Targets:
TPP E1 PDC AD..(10)
 
 
Bromo ALL-1(5)
 
 
NR LBD TR(4)
 
 
NR LBD ROR li..(4)
 
 
Menin(4)
 
 
BioAssay Types:
Literature(71)
 
 
 
 
Confirmatory(60)
 
 
 
Screening(5)
 
 
BioActivity Types:
Potency(57)
 
 
 
Kd(9)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 48    Data Row: 142   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46392800]
Kd 1.52Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Roles Of His291-Alpha And His146-Beta' In The Reductive Acylation Reaction Catalyzed By Human Branched-Chain Alpha-Ketoacid Dehydrogenase [gi:34810147]
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2
[SID46392800]
Kd 1.52Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Roles Of His291-Alpha And His146-Beta' In The Reductive Acylation Reaction Catalyzed By Human Branched-Chain Alpha-Ketoacid Dehydrogenase [gi:34810148]
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3
[SID46392801]
Kd 39.3Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Roles Of His291-Alpha And His146-Beta' In The Reductive Acylation Reaction Catalyzed By Human Branched-Chain Alpha-Ketoacid Dehydrogenase [gi:34810149]
View
4
[SID46392802]
Kd 47.1Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Roles Of His291-alpha And His146-beta' In The Reductive Acylation Reaction Catalyzed By Human Branched-chain Alpha-ketoacid Dehydrogenase [gi:34810151]
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5
[SID46393382]
Kd 104.8Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crosstalk Between Cofactor Binding And The Phosphorylation Loop Conformation In The Bckd Machine [gi:49259445]
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6
[SID46393382]
Kd 104.8Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Crosstalk Between Cofactor Binding And The Phosphorylation Loop Conformation In The Bckd Machine [gi:49259446]
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7
[SID46393386]
Kd 115Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crosstalk Between Cofactor Binding And The Phosphorylation Loop Conformation In The Bckd Machine [gi:404573635]
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8
[SID46393386]
Kd 115Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Crosstalk Between Cofactor Binding And The Phosphorylation Loop Conformation In The Bckd Machine [gi:49259451]
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9
[SID46393383]
Kd 134.8Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crosstalk Between Cofactor Binding And The Phosphorylation Loop Conformation In The Bckd Machine [gi:49259447]
View
10
[SID46393383]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: other]Chain A, Crosstalk Between Cofactor Binding And The Phosphorylation Loop Conformation In The Bckd Machine [gi:49259447]
View
11
[SID46393386]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: other]Chain A, Crosstalk Between Cofactor Binding And The Phosphorylation Loop Conformation In The Bckd Machine [gi:49259450]
View
12
[SID46392800]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: other]Chain A, Roles Of His291-Alpha And His146-Beta' In The Reductive Acylation Reaction Catalyzed By Human Branched-Chain Alpha-Ketoacid Dehydrogenase [gi:34810147]
View
13
[SID46393382]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: other]Chain A, Crosstalk Between Cofactor Binding And The Phosphorylation Loop Conformation In The Bckd Machine [gi:49259445]
View
14
[SID46392801]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: other]Chain A, Roles Of His291-Alpha And His146-Beta' In The Reductive Acylation Reaction Catalyzed By Human Branched-Chain Alpha-Ketoacid Dehydrogenase [gi:34810149]
View
15
[SID46392802]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: other]Chain A, Roles Of His291-alpha And His146-beta' In The Reductive Acylation Reaction Catalyzed By Human Branched-chain Alpha-ketoacid Dehydrogenase [gi:34810151]
View
16
[SID29216306]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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17
[SID29216306]
Potency 28.6954Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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18
[SID29216307]
Potency qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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19
[SID29216307]
Potency qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease [AID2101, Type: confirmatory]glucocerebrosidase [Homo sapiens] [gi:496369]
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20
[SID29216307]
Potency qHTS Assay for Inhibitors and Activators of Human alpha-Galactosidase From Spleen Homogenate [AID2107, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
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