Bookmark and Share
pirarubicin (CID 11296583) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(33)
 
 
Inactive(25)
 
 
Inconclusive(35)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
 
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
 
NR LBD Fxr(4)
 
 
 
NR LBD VDR(4)
 
 
BioAssay Types:
Confirmatory(67)
 
 
 
 
Summary(24)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(85)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 93    Data Row: 93   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144206155]
Potency-Replicate_1 0.0298qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
2
[SID144206155]
Potency-Replicate_1 0.1883qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
3
[SID144206155]
Potency 0.1884qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
4
[SID144206155]
Potency-Replicate_1 0.2371qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
5
[SID144206155]
Potency 0.335qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
6
[SID144206155]
Ratio Potency (uM) 0.604487qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
View
7
[SID144206155]
Potency-Replicate_1 0.6987qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
8
[SID144206155]
Potency-Replicate_1 0.8413qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
9
[SID144206155]
Potency 1.1175qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
View
10
[SID144206155]
Potency 1.2538qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
View
11
[SID144206155]
Potency-Replicate_1 1.6785qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
View
12
[SID144206155]
Potency-Replicate_1 1.8834qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
View
13
[SID144206155]
Potency-Replicate_1 2.371qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
View
14
[SID144206155]
ATAD5 Potency (uM) 2.66032qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
View
15
[SID144206155]
Potency-Replicate_1 3.0107qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway [AID720691, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
16
[SID144206155]
Ratio Potency (uM) 3.18904qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720719, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
View
17
[SID144206155]
Ratio Potency (uM) 3.37801qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
18
[SID144206155]
Ratio Potency (uM) 4.0967qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
View
19
[SID144206155]
Potency-Replicate_1 4.2163qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
20
[SID144206155]
Potency-Replicate_1 4.2485qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View