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BioActivity Data for Compound 174899-83-3 (CID 11258643)

BioActivity Outcomes:
Active(1)
 
 
Inactive(85)
 
 
Inconclusive(15)
 
 
Unspecified(62)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
 
NR LBD GR(4)
 
 
BioAssay Types:
Confirmatory(74)
 
 
 
 
 
Literature(60)
 
 
Summary(29)
 
 
 
BioAssay Categories:
Biochemical(2)
 
 
Toxicity(6)
 
 
 
 
Cell-based(60)
 
 
BioActivity Types:
Potency(95)
 
 
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 163    Data Row: 163   Total Pages: 9   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209815]
Potency-Replicate_1 61.1306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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2
[SID103718473]
IC50 333Inhibition of HIV1 recombinant integrase 3' processing activity using [32P]-radiolabeled full-length DNA as substrate after 1 hr by densitometric analysis [AID1117864, Type: confirmatory]Integrase [gi:82312013]
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3
[SID103718473]
IC50 333Inhibition of HIV1 recombinant integrase strand transfer activity using [32P]-radiolabeled full-length DNA as substrate after 1 hr by densitometric analysis [AID1117866, Type: confirmatory]Integrase [gi:82312013]
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4
[SID103718473]
Anticancer activity against human SF539 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455634, Type: Literature]
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5
[SID103718473]
Anticancer activity against human SF295 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455633, Type: Literature]
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6
[SID103718473]
Anticancer activity against human SF268 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455632, Type: Literature]
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7
[SID103718473]
Anticancer activity against human SW620 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455631, Type: Literature]
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8
[SID103718473]
Anticancer activity against human KM12 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455630, Type: Literature]
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9
[SID103718473]
Anticancer activity against human HT-29 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455629, Type: Literature]
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10
[SID103718473]
Anticancer activity against human HCT15 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455628, Type: Literature]
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11
[SID103718473]
Anticancer activity against human HCT116 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455627, Type: Literature]
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12
[SID103718473]
Anticancer activity against human HCC2998 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455626, Type: Literature]
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13
[SID103718473]
Anticancer activity against human NCI-H522 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455624, Type: Literature]
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14
[SID103718473]
Anticancer activity against human NCI-H322M cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455622, Type: Literature]
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15
[SID103718473]
Anticancer activity against human NCI-H23 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455621, Type: Literature]
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16
[SID103718473]
Anticancer activity against human NCI-H226 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455620, Type: Literature]
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17
[SID103718473]
Anticancer activity against human HOP92 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455619, Type: Literature]
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18
[SID103718473]
Anticancer activity against human EKVX cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455617, Type: Literature]
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19
[SID103718473]
Anticancer activity against human A549 cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455616, Type: Literature]
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20
[SID103718473]
Anticancer activity against human SR cells assessed cell growth at 10 uM after 48 hrs by sulforhodamine B assay relative to control [AID455615, Type: Literature]
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