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Taurine (CID 1123) - Compound BioActivity Data
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BioActivity Outcomes:
Active(7)
 
 
Inactive(1205)
 
 
Inconclusive(59)
 
 
Unspecified(16)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
7TM GPCR Srx(21)
 
 
p450(18)
 
 
NR LBD ER(17)
 
 
NR LBD AR(16)
 
 
 
BioAssay Types:
Confirmatory(750)
 
 
 
 
 
Screening(358)
 
 
Literature(84)
 
 
 
 
Summary(49)
 
 
 
 
BioActivity Types:
Potency(631)
 
 
 
 
 
IC50(14)
 
 
Ki(1)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 891    Data Row: 1287   Total Pages: 26   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209718]
Potency-Replicate_1 7.1266qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID144209718]
Ratio Potency (uM) 10.8697qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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3
[SID144209718]
Ratio Potency (uM) 13.6841qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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4
[SID144209718]
Potency-Replicate_1 22.5363qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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5
[SID144209718]
AhR Potency (uM) 28.3716qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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6
[SID144209718]
Potency-Replicate_1 28.3716qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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7
[SID144209718]
Potency-Replicate_1 31.8334qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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8
[SID103545120]
Ki 7800Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting [AID630741, Type: Literature]Proton-coupled amino acid transporter 1 [gi:51316800]
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9
[SID50104337]
Potency qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding [AID2675, Type: confirmatory]muscleblind-like protein 1 isoform a [Homo sapiens] [gi:41281591]
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10
[SID103545120]
Inhibition of Plasmodium falciparum FabI [AID309298, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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11
[SID46500351]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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12
[SID103545120]
Antimalarial activity against chloroquine-resistant, pyrimethamine-resistant Plasmodium falciparum K1 after 48 hrs [AID309299, Type: Literature]
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13
[SID103545120]
Antitrypanosomal activity against Trypanosoma brucei rhodesiense after 72 hrs by Alamar blue assay [AID309300, Type: Literature]
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14
[SID103545120]
Antitrypanosomal activity against Trypanosoma cruzi after 72 hrs [AID309301, Type: Literature]
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15
[SID103545120]
Antileishmanial activity against Leishmania donovani after 72 hrs by Alamar blue assay [AID309302, Type: Literature]
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16
[SID103545120]
Cytotoxicity against rat L6 cells after 72 hrs [AID309303, Type: Literature]
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17
[SID103545120]
Antineoplastic activity against mouse P388 cells at 100 mg/kg relative to control [AID355114, Type: Literature]
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18
[SID103545120]
In vivo antitumor activity against mouse P388 cells at 4 to 800 mg/ kg [AID402367, Type: Literature]
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19
[SID11113407]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
View
20
[SID17389723]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
21
[SID104171246]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
View
22
[SID103545120]
Inhibition of nitrogen-starved wild type sigma1278b yeast Gap1-mediated amino acid uptake at 5 mM after 60 secs relative to L-citrulline [AID500816, Type: Literature]
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23
[SID26751645]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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24
[SID104171246]
Potency 0.0011qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (3D7) proliferation [AID743344, Type: confirmatory]
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25
[SID90340929]
Potency 0.0107qHTS screen for enhancers of Arylsulfatase A (ASA1): LOPAC Validation Assay [AID720538, Type: confirmatory]arylsulfatase A [Homo sapiens] [gi:220983390]
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26
[SID90340929]
Potency 0.2668Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS [AID504845, Type: confirmatory]regulator of G-protein signaling 4 [Homo sapiens] [gi:86301163]
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27
[SID104171246]
Potency 1.3324qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (DD2) proliferation (Rep 2) [AID743346, Type: confirmatory]
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28
[SID144203828]
Potency 6.3096qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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29
[SID144209718]
Potency-Replicate_1 15.9545qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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30
[SID144203828]
Potency-Replicate_1 33.4915qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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31
[SID144209718]
Potency-Replicate_1 35.7177qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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32
[SID11111855]
Potency 39.8107qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19 [AID899, Type: confirmatory]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
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33
[SID11113407]
Potency qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19 [AID899, Type: confirmatory]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
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34
[SID11113407]
Cytochrome panel assay with activity outcomes [AID1851_1, Type: other]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
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35
[SID56320737]
uHTS identification of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay [AID588458, Type: screening]DNA (cytosine-5)-methyltransferase 1 isoform b [Homo sapiens] [gi:4503351]
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36
[SID90340929]
Potency HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Agonists [AID488981, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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37
[SID90340929]
Potency HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Potentiators [AID488982, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
View
38
[SID90340929]
Potency HTS Assay for Allosteric Agonists of the Human D1 Dopamine Receptor: Primary Screen for Antagonists [AID488983, Type: confirmatory]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
View
39
[SID46500351]
Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Antagonists [AID624463, Type: other]D(2) dopamine receptor isoform long [Homo sapiens] [gi:4503385]
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40
[SID46500351]
Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Potentiators [AID624464, Type: other]D(2) dopamine receptor isoform long [Homo sapiens] [gi:4503385]
View
41
[SID46500351]
Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Agonists [AID624465, Type: other]D(2) dopamine receptor isoform long [Homo sapiens] [gi:4503385]
View
42
[SID50104337]
Potency qHTS Validation Assay for Inhibitors of Human Galactokinase (GALK) [AID493189, Type: confirmatory]galactokinase [Homo sapiens] [gi:4503895]
View
43
[SID90340929]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: Diaphorase-coupled assay [AID743205, Type: confirmatory]glucokinase isoform 1 [Homo sapiens] [gi:4503951]
View
44
[SID90340929]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: ADP-Glo assay [AID743206, Type: confirmatory]glucokinase isoform 1 [Homo sapiens] [gi:4503951]
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45
[SID90340929]
Potency qHTS assay for inhibitors of recombinant human GCK-GKRP interaction: HTRF assay [AID743207, Type: confirmatory]glucokinase isoform 1 [Homo sapiens] [gi:4503951]
View
46
[SID56320737]
Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID602396, Type: screening]nuclear receptor subfamily 5 group A member 2 isoform 2 [Homo sapiens] [gi:4504343]
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47
[SID11111855]
Potency qHTS Assay for Modulators of Hemoglobin Beta Chain Splicing [AID925, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
View
48
[SID17389723]
Potency qHTS Assay for Modulators of Hemoglobin Beta Chain Splicing [AID925, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
View
49
[SID170465726]
Ratio Potency (uM) qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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50
[SID170465726]
Potency-Replicate_1 qHTS assay for small molecule activators of the heat shock response signaling pathway [AID743210, Type: confirmatory]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
View