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Taurine (CID 1123) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(1226)
 
 
Inconclusive(51)
 
 
Unspecified(16)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
7TM GPCR Srx(21)
 
 
p450(18)
 
 
NR LBD ER(17)
 
 
NR LBD TR(16)
 
 
BioAssay Types:
Confirmatory(752)
 
 
 
 
 
Screening(361)
 
 
Literature(90)
 
 
 
 
Summary(49)
 
 
 
 
BioActivity Types:
Potency(635)
 
 
 
 
 
IC50(14)
 
 
Ki(1)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 893    Data Row: 1298   Total Pages: 65   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144209718]
Potency-Replicate_1 7.1266qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID144209718]
Ratio Potency (uM) 10.8697qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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3
[SID144209718]
Ratio Potency (uM) 13.6841qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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4
[SID144209718]
AhR Potency (uM) 28.3716qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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5
[SID144209718]
Potency-Replicate_1 28.3716qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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6
[SID103545120]
Ki 7800Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting [AID630741, Type: Literature]Proton-coupled amino acid transporter 1 [gi:51316800]
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7
[SID50104337]
Potency qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding [AID2675, Type: confirmatory]muscleblind-like protein 1 isoform a [Homo sapiens] [gi:41281591]
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8
[SID46500351]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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9
[SID103545120]
Inhibition of Plasmodium falciparum FabI [AID309298, Type: Literature]Enoyl-acyl-carrier protein reductase precursor [gi:74844868]
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10
[SID103545120]
Antimalarial activity against chloroquine-resistant, pyrimethamine-resistant Plasmodium falciparum K1 after 48 hrs [AID309299, Type: Literature]
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11
[SID103545120]
Antitrypanosomal activity against Trypanosoma brucei rhodesiense after 72 hrs by Alamar blue assay [AID309300, Type: Literature]
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12
[SID103545120]
Antitrypanosomal activity against Trypanosoma cruzi after 72 hrs [AID309301, Type: Literature]
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13
[SID103545120]
Antileishmanial activity against Leishmania donovani after 72 hrs by Alamar blue assay [AID309302, Type: Literature]
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14
[SID103545120]
Cytotoxicity against rat L6 cells after 72 hrs [AID309303, Type: Literature]
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15
[SID103545120]
Antineoplastic activity against mouse P388 cells at 100 mg/kg relative to control [AID355114, Type: Literature]
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16
[SID103545120]
In vivo antitumor activity against mouse P388 cells at 4 to 800 mg/ kg [AID402367, Type: Literature]
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17
[SID17389723]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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18
[SID104171246]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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19
[SID103545120]
Inhibition of nitrogen-starved wild type sigma1278b yeast Gap1-mediated amino acid uptake at 5 mM after 60 secs relative to L-citrulline [AID500816, Type: Literature]
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20
[SID11113407]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
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