Bookmark and Share

BioActivity Data for Compound ataluren (CID 11219835)

BioActivity Outcomes:
Active(22)
 
 
Inactive(161)
 
 
Inconclusive(36)
 
 
Unspecified(45)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
 
 
7tm 4(5)
 
 
NR LBD Fxr(4)
 
 
 
BioAssay Types:
Literature(115)
 
 
 
 
Confirmatory(107)
 
 
 
 
Summary(27)
 
 
 
 
Screening(15)
 
 
 
BioAssay Categories:
In vivo(1)
 
 
Biochemical(2)
 
 
 
Toxicity(7)
 
 
 
ADME(8)
 
 
Cell-based(38)
 
 
 
 
BioActivity Types:
Potency(122)
 
 
 
 
AC50(6)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 203    Data Row: 264   Total Pages: 14   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144206184]
AhR Potency (uM) 0.00211317qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
2
[SID85852879]
Potency 0.0072Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
3
[SID144206184]
Potency-Replicate_1 0.0119qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
4
[SID144206184]
Potency-Replicate_1 0.0237qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
View
5
[SID144206184]
ATAD5 Potency (uM) 0.027644qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
View
6
[SID85852879]
Potency 0.3013Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
View
7
[SID144206184]
Potency-Replicate_1 0.4731qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
View
8
[SID85852879]
Potency 0.7079VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
View
9
[SID99460885]
Potency 2.6351qHTS Assay for Lipid Storage Modulators: 3T3L1 Assay against Probe and Analogs [AID652180, Type: confirmatory]
View
10
[SID144206184]
Potency 3.1623qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
View
11
[SID144206184]
Potency 8.9125qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
View
12
[SID144206184]
TR Potency (uM) 9.99848qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
13
[SID144206184]
Potency-Replicate_1 10.5909qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
14
[SID170466862]
Potency-Replicate_1 11.8823qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
View
15
[SID144206184]
Potency-Replicate_1 29.8493qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
View
16
[SID87334013]
Thermal Shift Assay for Inhibitors of FLuc (Firefly Luciferase, Photinus pyralis) in Absence of ATP [AID2229, Type: screening]Luciferase [Photinus pyralis] [gi:160794]
View
17
[SID87334013]
Thermal Shift Assay for Inhibitors of FLuc (Firefly Luciferase, Photinus pyralis) in Presence of ATP [AID2228, Type: screening]Luciferase [Photinus pyralis] [gi:160794]
View
18
[SID103563347]
Induction of ribosomal readthrough of dystrophin mRNA premature nonsense codons in primary muscle cell culture at 17 uM by immunocytometry [AID330976, Type: Literature]
View
19
[SID103563347]
Effect on production of dystrophin in mdx mouse muscle by Western blotting [AID330980, Type: Literature]
View
20
[SID103563347]
Increase in level of gamma sarcoplycan in mdx mouse muscle [AID330979, Type: Literature]
View