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SureCN3950928 (CID 11208735) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Unspecified(9)
 
 
Top Targets:
NR LBD PPAR(11)
 
 
 
BioAssay Types:
Literature(14)
 
 
 
BioActivity Types:
EC50(5)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 14    Data Row: 14   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103699290]
EC50 17.17Agonist activity at human PPARdelta expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay [AID736342, Type: Literature]Peroxisome proliferator-activated receptor delta [gi:417522]
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2
[SID103699290]
EC50 18.86Agonist activity at human PPARgamma expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay [AID736343, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432234]
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3
[SID103699290]
EC50 18.86Agonist activity at human PPARgamma assessed as luciferase activity by transactivation assay [AID439369, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432234]
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4
[SID103699290]
EC50 24.55Agonist activity at human PPARalpha assessed as luciferase activity by transactivation assay [AID439370, Type: Literature]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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5
[SID103699290]
EC50 24.55Agonist activity at human PPARalpha expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay [AID736344, Type: Literature]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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6
[SID103699290]
Agonist activity at human PPARdelta expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as beta-galactosidase activity at 25 uM measured after 48 hrs relative to vehicle control [AID736345, Type: Literature]Peroxisome proliferator-activated receptor delta [gi:417522]
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7
[SID103699290]
Agonist activity at human PPARalpha expressed in HEK293 cells co-transfected with PPRE assessed as beta-galactosidase signal at 25 uM after 48 hrs by reporter gene assay relative to control [AID439371, Type: Literature]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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8
[SID103699290]
Agonist activity at human PPARalpha expressed in HEK293 cells co-transfected with PPRE assessed as beta-galactosidase signal at 40 uM after 48 hrs by reporter gene assay relative to control [AID439372, Type: Literature]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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9
[SID103699290]
Agonist activity at human PPARgamma expressed in HEK293 cells co-transfected with PPRE assessed as beta-galactosidase signal at 5 uM after 48 hrs by reporter gene assay relative to control [AID439367, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432234]
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10
[SID103699290]
Agonist activity at human PPARgamma expressed in HEK293 cells co-transfected with PPRE assessed as beta-galactosidase signal at 25 uM after 48 hrs by reporter gene assay relative to control [AID439368, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432234]
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11
[SID103699290]
Cytotoxicity against HEK293 cells assessed as viable cells at 10 uM after 48 hrs by aqueous one solution cell proliferation assay relative to control [AID439373, Type: Literature]
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12
[SID103699290]
Cytotoxicity against HEK293 cells assessed as viable cells at 50 uM after 48 hrs by aqueous one solution cell proliferation assay relative to control [AID439376, Type: Literature]
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13
[SID103699290]
Cytotoxicity against human HEK293 cells assessed as cell viability at 10 uM measured after 48 hrs by MTS assay relative to vehicle control [AID736340, Type: Literature]
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14
[SID103699290]
Agonist activity at human PPARdelta expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as beta-galactosidase activity at 50 uM measured after 48 hrs relative to vehicle control [AID736341, Type: Literature]Peroxisome proliferator-activated receptor delta [gi:417522]
View